Evidence map›Paper›PMID 37620766›Full record

ArticleBMC genomics2023

Chromosome-level genome assembly of Babesia caballi reveals diversity of multigene families among Babesia species.

Akihiro Ochi, Taishi Kidaka, Hassan Hakimi, Masahito Asada, Junya Yamagishi

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Akihiro OchiEquine Research Institute, Japan Racing Association, Shimotsuke, Tochigi, Japan.
Taishi KidakaInternational Institute for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido, Japan.
Hassan HakimiNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.
Masahito AsadaNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.
Junya YamagishiInternational Institute for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido, Japan. junya@czc.hokudai.ac.jp.
Hokkaido University · JPJapan Racing Association · JPObihiro University of Agriculture and Veterinary Medicine · JPTexas A&M University · US

Funding

the Japan Racing Association 2-3272
6 · The paper itself

Abstract

backgroundBabesia caballi is an intraerythrocytic parasite from the phylum Apicomplexa, capable of infecting equids and causing equine piroplasmosis. However, since there is limited genome information available on B. caballi, molecular mechanisms involved in host specificity and pathogenicity of this species have not been fully elucidated yet.

resultsGenomic DNA from a B. caballi subclone was purified and sequenced using both Illumina and Nanopore technologies. The resulting assembled sequence consisted of nine contigs with a size of 12.9 Mbp, rendering a total of 5,910 protein-coding genes. The phylogenetic tree of Apicomplexan species was reconstructed using 263 orthologous genes. We identified 481 ves1-like genes and named "ves1c". In contrast, expansion of the major facilitator superfamily (mfs) observed in closely related B. bigemina and B. ovata species was not found in B. caballi. A set of repetitive units containing an open reading frame with a size of 297 bp was also identified.

conclusionsWe present a chromosome-level genome assembly of B. caballi. Our genomic data may contribute to estimating gene expansion events involving multigene families and exploring the evolution of species from this genus.

Indexed as

BabesiaAnimalsChromosomesHorsesMultigene FamilyOpen Reading FramesPhylogenyBabesia caballiComparative genomicsEquine babesiosisMultigene expansion

Identifiers

PMID37620766
PMCPMC10463595
OpenAlexW4386142088

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.