Evidence mapPaperPMID 37622666Full record

ArticleEuropean heart journal2023

2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure.

Theresa A McDonagh, Marco Metra, Marianna Adamo, Roy S Gardner, Andreas Baumbach, Michael Böhm, Haran Burri, Javed Butler, Jelena Čelutkienė, Ovidiu Chioncel and 21 more

Erratum issued 15 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in European heart journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It reports registered trial NCT07022379. Cited by 1,185 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,185citing papers in PubMed, 10 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07022379 completed

Temporal Trends and Determinants of Sodium-Glucose Cotransporter 2 Inhibitor Use in Patients Enrolled in a Nationwide Heart Failure Remote Monitoring Program

Ran2021Enrolled13,660Registered outcomes3Posted comparisons0ConditionsHeart Failure, Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF), Heart Failure With Preserved Ejection Fraction (HFpEF), Heart Failure With Reduced Ejection FractionArmsSGLT2 Inhibitor Use
PMID 36027570PMID 32865377PMID 31535829other papers from this trial
Open the trial in the graph
NCT06162247 recruitingnot on this map

Naples Federico II Intensive Cardiac Care Unit Registry (Naples FED2-ICCU Registry)

TypeobservationalSponsorFederico II UniversityRan2023 to 2033Enrolled5,000ConditionsAcute Cardiovascular Disease, Acute Coronary Syndrome, Acute Heart Failure, Cardiogenic Shock
NCT06645535 enrolling by invitationnot on this map

The Role and Mechanism of Gut Microbiota and Metabolites in Heart Failure With Preserved Ejection Fraction

Typeobservational_patient_registrySponsorThe First Affiliated Hospital with Nanjing Medical UniversityRan2022 to 2027Enrolled300ConditionsHFpEF - Heart Failure With Preserved Ejection Fraction
NCT06667128 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Optimization of Heart Failure (HF) Medical Therapy After Transcatheter Valve Intervention (TVI) in Patients With Heart Failure With Reduced Ejection Fraction (HFrEF)

TypeinterventionalSponsorIRCCS Ospedale San RaffaeleRan2025 to 2026Enrolled160ConditionsHeart Failure, Valvulopathy, Aortic Stenosis, Aortic Regurgitation DiseaseArmsRapid Uptitration of Guideline-Directed Medical Therapy, Elecsys® NT-proBNP - Roche Diagnostics, Rapid Up-Titration GDMT Group with Hospital Monitoring
NCT06668389 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

Sodium-Glucose Cotransporter 2 Inhibitors for Repaired Tetralogy of Fallot Patients for Enhancement of Cardio-Pulmonary Status Trial (STEPS Trial)

TypeinterventionalSponsorThe University of Hong KongRan2025 to 2026Enrolled106ConditionsCongenital Heart Disease, Repaired Tetralogy of Fallot (rTOF), Pulmonary Regurgitation, Sodium-glucose Cotransporter 2 (SGLT2) InhibitorArmsSGLT2 inhibitor (Dapagliflozin 10mg)
NCT06838507 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Incidence, Characterisation and Outcome-relevance of Perioperative SGLT2 Inhibitor Associated Ketoacidosis - A Multicentre Prospective Cohort Study

TypeobservationalSponsorHeinrich-Heine University, DuesseldorfRan2025 to 2026Enrolled2,000ConditionsSGLT2 Inhibitor, Ketoacidosis, Eugylcemic
NCT06927440 enrolling by invitationnot on this map

Development and Implementation of a National Multicenter Registry for Pediatric End-Stage Heart Failure in China

Typeobservational_patient_registrySponsorShanghai Jiao Tong University School of MedicineRan2023 to 2026Enrolled1,000ConditionsHeart Failure, Children
NCT06944405 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Implementation for Heart Failure Therapies Post-discharge Followed by CardiOSIgnal at HOME

TypeinterventionalSponsorPrecordior LtdRan2025 to 2026Enrolled65ConditionsHeart FailureArmsMechanocardiography
NCT07040995 nawithdrawnnot on this mapstarted 2025, after this paper: background citation

FASTTRACK - Facilitated Access to Optimized Treatment and Clinical Follow-Up for Elderly Patients by the Internal Medicine Heart Failure Outpatient Clinic - a Randomized Multicenter Prospective Study

TypeinterventionalSponsorRegion SkaneRan2025 to 2028Enrolled0ConditionsHeart FailureArmsSwift follow-up
NCT07403058 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Endovascular Ablation Of The Right Greater Splanchnic Nerve In Subjects Having Heart Failure With Reduced Ejection Fraction: Randomized Controlled Feasibility Trial

TypeinterventionalSponsorAxon Therapies, Inc.Ran2026 to 2028Enrolled50ConditionsHeart Failure With Reduced Ejection Fraction (HFrEF)ArmsRight Greater Splanchnic Nerve (GSN) ablation, Sham Control
NCT07451457 recruitingnot on this map

The Role of a Structured Patient Education Programme in the Complex Care of Patients With Heart Failure

TypeobservationalSponsorGottsegen National Cardiovascular InstituteRan2023 to 2026Enrolled1,000ConditionsHeart FailureArmsComplex, structured patient education programme
NCT07523646 phase4recruitingnot on this mapstarted 2026, after this paper: background citation

Anemia Therapy in Patients With Infective Endocarditis (POET-IRON)

TypeinterventionalSponsorRigshospitalet, DenmarkRan2026 to 2028Enrolled74ConditionsInfective Endocarditis (IE), Severe AnemiaArmsAdjunctive anemia therapy
NCT07539766 recruitingnot on this mapstarted 2025, after this paper: background citation

OBESE-HFpEF: Prevalence and Mediators of Heart Failure (Preserved Ejection Fraction) in the Dutch Obesity Clinic South - Towards Preventing Obesity Related HFpEF''

Typeobservational_patient_registrySponsorZuyderland Medisch CentrumRan2025 to 2029Enrolled250ConditionsHeart Failure and Preserved Ejection Fraction, Obesity (Disorder), Heart Failure
NCT07623083 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluation of a Treatment Algorithm for the Management of TAVI Patients With Significant Concomitant Mitral or Tricuspid Regurgitation

TypeobservationalSponsorJosep Rodes-CabauRan2026 to 2034Enrolled300ConditionsAortic Stenosis, Mitral Regurgitation, Tricuspid Regurgitation, Transcatheter Aortic Valve Implantation (TAVI)
NCT07642921 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Phenotyping Heart Failure With Preserved Ejection Fraction (HFpEF) Using Echocardiographic, Clinical, and Biomarker Parameters

Typeobservational_patient_registrySponsorUniversity Of PerugiaRan2026 to 2029Enrolled500ConditionsHeart Failure With Preserved Ejection Fraction (HFPEF)
3 · Its place in the literature

Who cites it

1,185 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Guideline
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  8. Guideline
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  11. Early palliative care in heart failure shows neutral effects across EF subtypes: an exploratory EPCHF secondary analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
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  20. Heart failure burden and care among cardiology inpatients: insights from the Hellenic Cardiorenal Morbidity Snapshot (HECMOS) study.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article

1,125 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

31 authors.

Theresa A McDonagh(Chairperson) (United Kingdom).ORCID 0000-0003-1305-9602
Marco Metra(Chairperson) (Italy).ORCID 0000-0001-6691-8568
Marianna Adamo(Task Force Co-ordinator) (Italy).ORCID 0000-0002-3855-1815
Roy S Gardner(Task Force Co-ordinator) (United Kingdom).ORCID 0000-0002-6792-6671
Andreas Baumbach(United Kingdom).ORCID 0000-0001-7707-2254
Michael Böhm(Germany).ORCID 0000-0002-2976-2514
Haran Burri(Switzerland).ORCID 0000-0002-4393-5338
Javed Butler(United States of America).ORCID 0000-0001-7683-4720
Jelena Čelutkienė(Lithuania).ORCID 0000-0003-3562-9274
Ovidiu Chioncel(Romania).ORCID 0000-0002-3197-3628
John G F Cleland(United Kingdom).ORCID 0000-0002-1471-7016
Maria Generosa Crespo-Leiro(Spain).ORCID 0000-0002-3085-167X
Dimitrios Farmakis(Greece).ORCID 0000-0001-8364-3447
Martine Gilard(France).ORCID 0000-0002-2794-7953
Stephane Heymans(Netherlands).ORCID 0000-0001-9477-7803
Arno W Hoes(Netherlands).ORCID 0000-0002-8747-6479
Tiny Jaarsma(Sweden).ORCID 0000-0002-4197-4026
Ewa A Jankowska(Poland).ORCID 0000-0002-9202-432X
Mitja Lainscak(Slovenia).ORCID 0000-0002-5922-4098
Carolyn S P Lam(Singapore).ORCID 0000-0003-1903-0018
Alexander R Lyon(United Kingdom).ORCID 0000-0001-8026-840X
John J V McMurray(United Kingdom).ORCID 0000-0002-6317-3975
Alexandre Mebazaa(France).ORCID 0000-0001-8715-7753
Richard Mindham(United Kingdom).ORCID 0000-0003-1116-5284
Claudio Muneretto(Italy).ORCID 0000-0003-2656-4544
Massimo Francesco Piepoli(Italy).ORCID 0000-0003-1124-234X
Susanna Price(United Kingdom).ORCID 0000-0002-6425-3360
Giuseppe M C Rosano(United Kingdom).
Frank Ruschitzka(Switzerland).ORCID 0000-0001-5972-0596
Anne Kathrine Skibelund(Denmark).
ESC Scientific Document Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Heart FailureHumansStroke VolumeAcute heart failureChronic kidney disease hospitalizationComorbiditiesDiagnosisEjection fractionGuidelinesHeart failureMultidisciplinary managementNatriuretic peptidesNeurohormonal antagonistsPharmacotherapyPrevention

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

and 9 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.