Evidence map›Paper›PMID 37622909›Full record

ReviewBiosensors2023

Electrochemical Wearable Biosensors and Bioelectronic Devices Based on Hydrogels: Mechanical Properties and Electrochemical Behavior.

Mohsen Saeidi, Hossein Chenani, Mina Orouji, MahsaSadat Adel Rastkhiz, Nafiseh Bolghanabadi, Shaghayegh Vakili, Zahra Mohamadnia, Amir Hatamie, Abdolreza Arash Simchi

Abstract readReview
In one paragraph

Review in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  6. Penetration depth of cold atmospheric plasma into biological tissue: a review.Frontiers in bioengineering and biotechnology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohsen SaeidiDepartment of Materials Science and Engineering, Sharif University of Technology, Tehran 14588-89694, Iran.ORCID 0000-0001-5430-3339
Hossein ChenaniDepartment of Materials Science and Engineering, Sharif University of Technology, Tehran 14588-89694, Iran.ORCID 0009-0009-6924-6491
Mina OroujiDepartment of Materials Science and Engineering, Sharif University of Technology, Tehran 14588-89694, Iran.
MahsaSadat Adel RastkhizDepartment of Materials Science and Engineering, Sharif University of Technology, Tehran 14588-89694, Iran.
Nafiseh BolghanabadiDepartment of Materials Science and Engineering, Sharif University of Technology, Tehran 14588-89694, Iran.
Shaghayegh VakiliPolymer Research Laboratory, Department of Chemistry, Faculty of Science, University of Zanjan, Zanjan 45371-38791, Iran.
Zahra MohamadniaDepartment of Chemistry, Institute for Advanced Studies in Basic Science (IASBS), Gava Zang, Zanjan 45137-66731, Iran.
Amir HatamieDepartment of Chemistry, Institute for Advanced Studies in Basic Science (IASBS), Gava Zang, Zanjan 45137-66731, Iran.
Abdolreza Arash SimchiDepartment of Materials Science and Engineering, Sharif University of Technology, Tehran 14588-89694, Iran.ORCID 0000-0002-9111-2977

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogel-based wearable electrochemical biosensors (HWEBs) are emerging biomedical devices that have recently received immense interest. The exceptional properties of HWEBs include excellent biocompatibility with hydrophilic nature, high porosity, tailorable permeability, the capability of reliable and accurate detection of disease biomarkers, suitable device-human interface, facile adjustability, and stimuli responsive to the nanofiller materials. Although the biomimetic three-dimensional hydrogels can immobilize bioreceptors, such as enzymes and aptamers, without any loss in their activities. However, most HWEBs suffer from low mechanical strength and electrical conductivity. Many studies have been performed on emerging electroactive nanofillers, including biomacromolecules, carbon-based materials, and inorganic and organic nanomaterials, to tackle these issues. Non-conductive hydrogels and even conductive hydrogels may be modified by nanofillers, as well as redox species. All these modifications have led to the design and development of efficient nanocomposites as electrochemical biosensors. In this review, both conductive-based and non-conductive-based hydrogels derived from natural and synthetic polymers are systematically reviewed. The main synthesis methods and characterization techniques are addressed. The mechanical properties and electrochemical behavior of HWEBs are discussed in detail. Finally, the prospects and potential applications of HWEBs in biosensing, healthcare monitoring, and clinical diagnostics are highlighted.

Indexed as

NanocompositesWearable Electronic DevicesBiomimeticsCarbonHumansHydrogelsCarbonHydrogelsbiocompatible polymerelectroactive hydrogelelectrochemistryflexible biosensorsmechanical behavior

Identifiers

PMID37622909
PMCPMC10452289

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.