Evidence map›Paper›PMID 37623338›Full record

ReviewJournal of cardiovascular development and disease2023

Comparative Analysis of Heart Regeneration: Searching for the Key to Heal the Heart-Part I: Experimental Injury Models to Study Cardiac Regeneration.

Juan Manuel Castillo-Casas, Sheila Caño-Carrillo, Cristina Sánchez-Fernández, Diego Franco, Estefanía Lozano-Velasco

Abstract readReview
In one paragraph

Review in Journal of cardiovascular development and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Juan Manuel Castillo-CasasCardiovascular Development Group, Department of Experimental Biology, University of Jaén, 23071 Jaén, Spain.ORCID 0009-0005-0984-3543
Sheila Caño-CarrilloCardiovascular Development Group, Department of Experimental Biology, University of Jaén, 23071 Jaén, Spain.ORCID 0000-0002-3746-877X
Cristina Sánchez-FernándezCardiovascular Development Group, Department of Experimental Biology, University of Jaén, 23071 Jaén, Spain.
Diego FrancoCardiovascular Development Group, Department of Experimental Biology, University of Jaén, 23071 Jaén, Spain.ORCID 0000-0002-5669-7164
Estefanía Lozano-VelascoCardiovascular Development Group, Department of Experimental Biology, University of Jaén, 23071 Jaén, Spain.ORCID 0000-0002-5615-2754

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases are the leading cause of death worldwide, among which, ischemic heart disease is the most prevalent. Myocardial infarction results from occlusion of a coronary artery, which leads to an insufficient blood supply to the myocardium. As is well known, the massive loss of cardiomyocytes cannot be solved due the limited regenerative ability of the adult mammalian heart. In contrast, some lower vertebrate species can regenerate the heart after injury; their study has disclosed some of the involved cell types, molecular mechanisms and signaling pathways during the regenerative process. In this two-part review, we discuss the current state of the principal response in heart regeneration, where several involved processes are essential for full cardiac function in recovery.

Indexed as

cardiac diseasecell cyclefibrosisheart regenerationhypoxiainflammationmetabolismmolecular pathwaysmyocardial infarction

Identifiers

PMID37623338
PMCPMC10455172

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.