Evidence map›Paper›PMID 37624243›Full record

ArticleToxins2023

Mycolactone A vs. B: Multiscale Simulations Reveal the Roles of Localization and Association in Isomer-Specific Toxicity.

John D M Nguyen, Gabriel C A da Hora, Jessica M J Swanson

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

John D M NguyenDepartment of Chemistry, University of Utah, Salt Lake City, UT 84112, USA.ORCID 0000-0003-2249-2221
Gabriel C A da HoraDepartment of Chemistry, University of Utah, Salt Lake City, UT 84112, USA.ORCID 0000-0002-6372-6533
Jessica M J SwansonDepartment of Chemistry, University of Utah, Salt Lake City, UT 84112, USA.
University of Utah · US

Funding

Integrating Stochasticity into Biomolecular Mechanisms: A New Direction for Biomolecular ModelingR35GM143117 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI SWANSON, JESSICA · 2021 to 2025
$1.9M
NIGMS NIH HHS R35 GM143117
6 · The paper itself

Abstract

Mycolactone is an exotoxin produced by

Indexed as

Buruli UlcerCryoelectron MicroscopyHumansMacrolidesSEC Translocation ChannelsMacrolidesmycolactonemycolactone ASEC Translocation ChannelsBuruli ulcerER membraneisomeric specificitymembrane permeationmolecular dynamicsmycolactoneSec61 translocon

Identifiers

PMID37624243
PMCPMC10467071
OpenAlexW4385483184

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.