Evidence map›Paper›PMID 37624256›Full record

ReviewToxins2023

Gut Microbiota Interventions to Retain Residual Kidney Function.

Denise Mafra, Julie A Kemp, Natalia A Borges, Michelle Wong, Peter Stenvinkel

Open access · goldAbstract readReview
In one paragraph

Review in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Microbiota-gut-kidney axis in health and renal disease.International journal of biological sciences · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Harnessing Evolution and Biomimetics to Enhance Planetary Health: Kidney Insights.Journal of the American Society of Nephrology : JASN · 2025
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Gut Microbiota in Patients Receiving Dialysis: A Review.Pathogens (Basel, Switzerland) · 2024
    Review
  16. Article
  17. Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Denise MafraGraduate Program in Nutrition Sciences, Fluminense Federal University (UFF), Niteroi 24020-140, Brazil.ORCID 0000-0001-6752-6056
Julie A KempGraduate Program in Nutrition Sciences, Fluminense Federal University (UFF), Niteroi 24020-140, Brazil.ORCID 0000-0001-6739-8832
Natalia A BorgesInstitute of Nutrition, Rio de Janeiro State University (UERJ), Rio de Janeiro 20550-170, Brazil.
Michelle WongDivision of Nephrology, Department of Medicine, University of British Columbia, Vancouver, BC V6T 1Z1, Canada.ORCID 0000-0002-1334-0763
Peter StenvinkelKarolinska Institutet Innovations, 171 65 Stockholm, Sweden.ORCID 0000-0002-8785-4820
Karolinska Institutet Innovations (Sweden) · SEUniversidade do Estado do Rio de Janeiro · BRUniversidade Federal do Rio de Janeiro · BRUniversidade Federal Fluminense · BRUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Residual kidney function for patients with chronic kidney disease (CKD) is associated with better quality of life and outcome; thus, strategies should be implemented to preserve kidney function. Among the multiple causes that promote kidney damage, gut dysbiosis due to increased uremic toxin production and endotoxemia need attention. Several strategies have been proposed to modulate the gut microbiota in these patients, and diet has gained increasing attention in recent years since it is the primary driver of gut dysbiosis. In addition, medications and faecal transplantation may be valid strategies. Modifying gut microbiota composition may mitigate chronic kidney damage and preserve residual kidney function. Although various studies have shown the influential role of diet in modulating gut microbiota composition, the effects of this modulation on residual kidney function remain limited. This review discusses the role of gut microbiota metabolism on residual kidney function and vice versa and how we could preserve the residual kidney function by modulating the gut microbiota balance.

Indexed as

Gastrointestinal MicrobiomeDysbiosisFecal Microbiota TransplantationHumansKidneyQuality of Lifechronic kidney diseasegut microbiotainterventionsnutritionresidual kidney function

Identifiers

PMID37624256
PMCPMC10467110
OpenAlexW4385759385

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.