Evidence map›Paper›PMID 37624889›Full record

ArticleScience advances2023

Leptin receptor neurons in the dorsomedial hypothalamus input to the circadian feeding network.

Qijun Tang, Elizabeth Godschall, Charles D Brennan, Qi Zhang, Ruei-Jen Abraham-Fan, Sydney P Williams, Taha Buğra Güngül, Roberta Onoharigho, Aleyna Buyukaksakal, Ricardo Salinas and 7 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. A direct SCN-to-DMH output pathway organizes circadian behavioral timing.bioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Knockdown ofFrontiers in physiology · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Qijun TangDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.ORCID 0000-0002-5958-4616
Elizabeth GodschallDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.ORCID 0000-0002-9719-5048
Charles D BrennanDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.
Qi ZhangDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.ORCID 0000-0002-5195-511X
Ruei-Jen Abraham-FanDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.
Sydney P WilliamsDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.
Taha Buğra GüngülDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.ORCID 0000-0001-7632-4456
Roberta OnoharighoDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.ORCID 0000-0002-7321-6369
Aleyna BuyukaksakalDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.ORCID 0009-0004-5970-1001
Ricardo SalinasDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.ORCID 0009-0009-2569-3791
Isabelle R SajoniaDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.
Joey J OlivieriDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.
O Yipkin CalhanDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.ORCID 0000-0001-5630-6533
Christopher D DeppmannDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.ORCID 0000-0002-6591-1767
John N CampbellDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.ORCID 0000-0002-3943-8312
Brandon PodymaDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.ORCID 0000-0002-0849-8726
Ali D GülerDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.ORCID 0000-0001-8218-850X
University of Virginia · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007267 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GARCIA-BLANCO, MARIANO A. · 1985 to 2024
$13.4M
TRAINING IN THE PHARMACOLOGICAL SCIENCEST32GM007055 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI LYNCH, KEVIN R. · 1985 to 2022
$7.2M
Molecular and Functional Taxonomy of Cardiovagal NeuronsR01HL153916 · NHLBI · UNIVERSITY OF VIRGINIA · PI CAMPBELL, JOHN NELSON · 2021 to 2025
$3.1M
Interplay between circadian and reward pathways in homeostatic response and pathologyR35GM140854 · NIGMS · UNIVERSITY OF VIRGINIA · PI Ali Guler · 2021 to 2026
$3.0M
Regulation of central circadian rhythms by dopamineR01GM121937 · NIGMS · UNIVERSITY OF VIRGINIA · PI GULER, ALI · 2016 to 2020
$2.3M
Identification of cell-type specific visual circuits in the ventral lateral geniculate nucleusR21EY033528 · NEI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI CAMPBELL, JOHN N, FOX, MICHAEL A · 2022 to 2023
$441k
NEI NIH HHS R21 EY033528NHLBI NIH HHS R01 HL153916NIGMS NIH HHS R01 GM121937NIGMS NIH HHS R35 GM140854NIGMS NIH HHS T32 GM007055NIGMS NIH HHS T32 GM007267
6 · The paper itself

Abstract

Salient cues, such as the rising sun or availability of food, entrain biological clocks for behavioral adaptation. The mechanisms underlying entrainment to food availability remain elusive. Using single-nucleus RNA sequencing during scheduled feeding, we identified a dorsomedial hypothalamus leptin receptor-expressing (DMH

Indexed as

Circadian ClocksReceptors, LeptinAcclimatizationHypothalamusSuprachiasmatic NucleusReceptors, Leptin

Identifiers

PMID37624889
PMCPMC10456850
OpenAlexW4386156467

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.