Evidence map›Paper›PMID 37626178›Full record

ArticleScientific reports2023

A pan-cancer analysis of potassium channel tetramerization domain containing 12 in human cancer.

Pan Liu, Zhilan Liu, Qiankun Luo, Qiang Fu, Xu Zhang, Pengfei Yu, Shuai Zhou, Yingying Wang, Jiali Zhang, Song Chen and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Pan LiuDepartment of Hepato-Biliary-Pancreatic Surgery, Zhengzhou University People's Hospital (Henan Provincial People's Hospital), No. 7 Weiwu Road, Jinshui District, Zhengzhou, 450000, China.
Zhilan LiuHenan University of Chinese Medicine, Zhengzhou, 450000, China.
Qiankun LuoDepartment of Hepato-Biliary-Pancreatic Surgery, Zhengzhou University People's Hospital (Henan Provincial People's Hospital), No. 7 Weiwu Road, Jinshui District, Zhengzhou, 450000, China.
Qiang FuDepartment of Hepato-Biliary-Pancreatic Surgery, Zhengzhou University People's Hospital (Henan Provincial People's Hospital), No. 7 Weiwu Road, Jinshui District, Zhengzhou, 450000, China.
Xu ZhangDepartment of Hepato-Biliary-Pancreatic Surgery, Zhengzhou University People's Hospital (Henan Provincial People's Hospital), No. 7 Weiwu Road, Jinshui District, Zhengzhou, 450000, China.
Pengfei YuDepartment of Hepato-Biliary-Pancreatic Surgery, Zhengzhou University People's Hospital (Henan Provincial People's Hospital), No. 7 Weiwu Road, Jinshui District, Zhengzhou, 450000, China.
Shuai ZhouTranslational Research Institute, Zhengzhou University People's Hospital, Zhengzhou, 450003, China.
Yingying WangAcademy of Medical Sciences, Zhengzhou University, Zhengzhou, 450003, China.
Jiali ZhangAcademy of Medical Sciences, Zhengzhou University, Zhengzhou, 450003, China.
Song ChenTranslational Research Institute, Zhengzhou University People's Hospital, Zhengzhou, 450003, China.
Hongwei ZhangDepartment of Hepato-Biliary-Pancreatic Surgery, Zhengzhou University People's Hospital (Henan Provincial People's Hospital), No. 7 Weiwu Road, Jinshui District, Zhengzhou, 450000, China. hwzhang666@126.com.
Qinghai ZhuZhumadian Central Hospital, No. 747, Zhonghua Road, Zhumadian, 463000, China. liuyedaodoctor@163.com.
Tao QinDepartment of Hepato-Biliary-Pancreatic Surgery, Zhengzhou University People's Hospital (Henan Provincial People's Hospital), No. 7 Weiwu Road, Jinshui District, Zhengzhou, 450000, China. qtgoodfreecn@zzu.edu.cn.
Zhengzhou University · CNHenan Provincial People's Hospital · CNFirst Affiliated Hospital of Henan University · CNZhumadian Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abnormal expression of the potassium channel tetramerization domain containing 12 (KCTD12) is closely related to the occurrence and development of various tumors, but a pan-cancer analysis of KCTD12 has not yet been conducted. We explored the association between KCTD12 and more than 30 human malignancies using The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. First, the mRNA and protein levels of KCTD12 were examined and their correlations with tumor stage and survival were explored. Second, we analyzed the infiltration of CD8

Indexed as

AdenocarcinomaBreast NeoplasmsLung NeoplasmsPancreatic NeoplasmsUterine Cervical NeoplasmsFemaleHumansProteinsKCTD12 protein, humanProteins

Identifiers

PMID37626178
PMCPMC10457314
OpenAlexW4386167709

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.