Evidence map›Paper›PMID 37626475›Full record

ArticleClinical cardiology2023

Safety and efficacy of catheter ablation of atrial fibrillation in the very elderly (≥80 years old): Insights from the UC San Diego AF Ablation Registry.

Omar M Aldaas, Douglas Darden, Praneet S Mylavarapu, Amer M Aldaas, Frederick T Han, Kurt S Hoffmayer, David Krummen, Gordon Ho, Farshad Raissi, Gregory K Feld and 1 more

Open access · goldAbstract read
In one paragraph

Article in Clinical cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Outcomes of catheter ablation for atrial fibrillation in octogenarians: a systematic review and meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  2. Clinical outcomes after catheter ablation for atrial fibrillation in elderly patients: a meta-analysis with time-to-event data reconstruction.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Disparities in the access to atrial fibrillation ablation in Denmark: who gets ablated, who neglected?Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  7. Response to Letter to the Editor.Clinical cardiology · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Omar M AldaasDivision of Cardiac Electrophysiology at the University of California San Diego Health System, La Jolla, California, USA.ORCID http://orcid.org/0000-0001-6542-1621
Douglas DardenDivision of Cardiac Electrophysiology at the University of California San Diego Health System, La Jolla, California, USA.
Praneet S MylavarapuDivision of Cardiac Electrophysiology at the University of California San Diego Health System, La Jolla, California, USA.
Amer M AldaasA. T. Still University School of Osteopathic Medicine, Mesa, Arizona, USA.
Frederick T HanDivision of Cardiac Electrophysiology at the University of California San Diego Health System, La Jolla, California, USA.
Kurt S HoffmayerDivision of Cardiac Electrophysiology at the University of California San Diego Health System, La Jolla, California, USA.
David KrummenDivision of Cardiac Electrophysiology at the University of California San Diego Health System, La Jolla, California, USA.
Gordon HoDivision of Cardiac Electrophysiology at the University of California San Diego Health System, La Jolla, California, USA.
Farshad RaissiDivision of Cardiac Electrophysiology at the University of California San Diego Health System, La Jolla, California, USA.
Gregory K FeldDivision of Cardiac Electrophysiology at the University of California San Diego Health System, La Jolla, California, USA.
Jonathan C HsuDivision of Cardiac Electrophysiology at the University of California San Diego Health System, La Jolla, California, USA.
UC San Diego Health System · USA.T. Still University · US

Funding

The Marouf Family and The Butler and Gratt Family
6 · The paper itself

Abstract

backgroundCatheter ablation improves outcomes in symptomatic atrial fibrillation (AF) patients. However, its safety and efficacy in the very elderly (≥80 years old) is not well described. HYPOTHESIS: Ablation of AF in the very elderly is safe and effective.

methodsWe performed a retrospective study of all patients who underwent catheter ablation enrolled in the University of California, San Diego AF Ablation Registry. The primary outcome was freedom from atrial arrhythmias on or off antiarrhythmic drugs (AADs).

resultsOf 847 patients, 42 (5.0%) were 80 years of age or greater with a median age of 81.5 (80-82.3) and 805 (95.0%) were less than 80 years of age with a median age of 64.4 (57.6-70.2). Among those who were ≥80 years old, 29 were undergoing de novo ablation (69.0%), whereas in the younger cohort, 518 (64.5%) were undergoing de novo ablation (p = .548). There were no statistically significant differences in fluoroscopy (p = .406) or total procedure times (p = .076), AAD use (p = .611), or procedural complications (p = .500) between groups. After multivariable adjustment, there were no statistically significant differences in recurrence of any atrial arrhythmias on or off AAD (adjusted hazard ratio [AHR]: 0.75; 95% confidence interval [CI]: 0.45-1.23; p = .252), all-cause hospitalizations (AHR: 0.86; 95% CI: 0.46-1.60; p = .626), or all-cause mortality (AHR: 4.48; 95% CI: 0.59-34.07; p = .147) between the very elderly and the younger cohort.

conclusionIn this registry analysis, catheter ablation of AF appears similarly effective and safe in patients 80 years or older when compared to a younger cohort.

Indexed as

Atrial FibrillationCatheter AblationAgedAged, 80 and overAnti-Arrhythmia AgentsHumansRecurrenceRegistriesRetrospective StudiesTreatment OutcomeAnti-Arrhythmia Agentsatrial fibrillationcatheter ablationcomplicationshospitalizationsmortalityvery elderly

Identifiers

PMID37626475
PMCPMC10716336
OpenAlexW4386188172

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.