Evidence map›Paper›PMID 37626655›Full record

ReviewBiomedicines2023

Role of Fork-Head Box Genes in Breast Cancer: From Drug Resistance to Therapeutic Targets.

Sadaf, Ali Hazazi, Samia S Alkhalil, Ahad Amer Alsaiari, Amal F Gharib, Hayaa M Alhuthali, Shanika Rana, Abdulaziz A Aloliqi, Alaa Abdulaziz Eisa, Mohammad Raghibul Hasan and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. The Role of the Fox Gene in Breast Cancer Progression.International journal of molecular sciences · 2025
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 2 countries.

SadafDepartment of Biotechnology, Jamia Millia Islamia, New Delhi 110025, India.
Ali HazaziDepartment of Pathology and Laboratory Medicine, Security Forces Hospital Program, Riyadh 11481, Saudi Arabia.
Samia S AlkhalilDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Shaqra University, Alquwayiyah 11961, Saudi Arabia.ORCID 0000-0001-5811-7592
Ahad Amer AlsaiariDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi Arabia.ORCID 0000-0003-4117-5811
Amal F GharibDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi Arabia.
Hayaa M AlhuthaliDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi Arabia.ORCID 0000-0001-5999-081X
Shanika RanaSchool of Biosciences, Apeejay Stya University, Gurugram 122003, India.
Abdulaziz A AloliqiDepartment of Medical Biotechnology, College of Applied Medical Sciences, Qassim University, Buraydah 52571, Saudi Arabia.ORCID 0000-0002-7108-0541
Alaa Abdulaziz EisaDepartment of Medical Laboratories Technology, College of Applied Medical Sciences, Taibah University, Medina 30002, Saudi Arabia.
Mohammad Raghibul HasanDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Shaqra University, Riyadh 15342, Saudi Arabia.ORCID 0000-0001-9099-9716
Kapil DevDepartment of Biotechnology, Jamia Millia Islamia, New Delhi 110025, India.
Taif University · SADepartment of Biotechnology · INShaqra University · SAApeejay Stya University · INQassim University · SASecurity Forces Hospital · SATaibah University · SA

Funding

Indian Council of Medical Research 3/2/3/8/2022-NCD-III
6 · The paper itself

Abstract

Breast cancer has been acknowledged as one of the most notorious cancers, responsible for millions of deaths around the globe. Understanding the various factors, genetic mutations, comprehensive pathways, etc., that are involved in the development of breast cancer and how these affect the development of the disease is very important for improving and revitalizing the treatment of this global health issue. The forkhead-box gene family, comprising 19 subfamilies, is known to have a significant impact on the growth and progression of this cancer. The article looks into the various forkhead genes and how they play a role in different types of cancer. It also covers their impact on cancer drug resistance, interaction with microRNAs, explores their potential as targets for drug therapies, and their association with stem cells.

Indexed as

breast cancerdrug resistanceforkhead genesforkhead proteinsFOXAFOXCFOXM1FOXOFOXPmiRNAsstem cells

Identifiers

PMID37626655
PMCPMC10452497
OpenAlexW4385446991

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.