Evidence map›Paper›PMID 37626748›Full record

ArticleBiomedicines2023

Detailed Mechanisms Underlying Neutrophil Bactericidal Activity against

Zachary Tsai, Kyle A Carver, Henry H Gong, Kosuke Kosai, Jane C Deng, Matthew J Worley

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zachary TsaiDivision of Pulmonary and Critical Care Medicine, University of Michigan School of Medicine, Ann Arbor, MI 48105, USA.
Kyle A CarverDivision of Pulmonary and Critical Care Medicine, University of Michigan School of Medicine, Ann Arbor, MI 48105, USA.
Henry H GongResearch Service and Pulmonary Section, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI 48105, USA.
Kosuke KosaiDivision of Pulmonary and Critical Care Medicine, University of Michigan School of Medicine, Ann Arbor, MI 48105, USA.
Jane C DengDivision of Pulmonary and Critical Care Medicine, University of Michigan School of Medicine, Ann Arbor, MI 48105, USA.
Matthew J WorleyDivision of Pulmonary and Critical Care Medicine, University of Michigan School of Medicine, Ann Arbor, MI 48105, USA.

Funding

RESEARCH TRAINING IN EXPERIMENTAL IMMUNOPATHOLOGYT32AI007413 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Bethany B. Moore · 1993 to 2026
$9.8M
Mechanisms to augment primary immunity in agingR01AG028082 · NIA · YALE UNIVERSITY · PI DENG, JANE C · 2007 to 2023
$6.9M
BLRD VA I01 BX004565NIAID NIH HHS T32 AI007413NIA NIH HHS R01 AG028082
6 · The paper itself

Abstract

Neutrophils are an essential cellular component of innate immunity and control bacterial infections through a combination of intracellular and extracellular killing methods. Although the importance of neutrophils has been established, the exact methods used to handle particular bacterial challenges and the efficiency of bacterial killing remain not well understood. In this study, we addressed how neutrophils eliminate

Indexed as

bactericidaldegranulationinnate immunityneutrophilneutrophil extracellular trapphagocytosisreactive oxygen speciesStreptococcus pneumoniaeToll-like receptor

Identifiers

PMID37626748
PMCPMC10452576

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.