Evidence map›Paper›PMID 37626801›Full record

ArticleBiomedicines2023

Comparison of the Fecal Bacteriome of HIV-Positive and HIV-Negative Older Adults.

Matilde Sánchez-Conde, Claudio Alba, Irma Castro, Fernando Dronda, Margarita Ramírez, Rebeca Arroyo, Santiago Moreno, Juan Miguel Rodríguez, Fátima Brañas

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Matilde Sánchez-CondeInfectious Diseases Department, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), 28034 Madrid, Spain.
Claudio AlbaDepartment of Nutrition and Food Science, Complutense University of Madrid, 28040 Madrid, Spain.
Irma CastroDepartment of Nutrition and Food Science, Complutense University of Madrid, 28040 Madrid, Spain.
Fernando DrondaInfectious Diseases Department, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), 28034 Madrid, Spain.
Margarita RamírezInfectious Diseases Department, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0002-4666-0114
Rebeca ArroyoDepartment of Nutrition and Food Science, Complutense University of Madrid, 28040 Madrid, Spain.
Santiago MorenoInfectious Diseases Department, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), 28034 Madrid, Spain.ORCID 0000-0002-2843-1094
Juan Miguel RodríguezDepartment of Nutrition and Food Science, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-1285-9686
Fátima BrañasGeriatric Department, Hospital Universitario Infanta Leonor, 28031 Madrid, Spain.ORCID 0000-0001-7609-5382
Universidad Complutense de Madrid · ESInstituto Ramón y Cajal de Investigación Sanitaria · ESHospital General Universitario Gregorio Marañón · ESHospital Universitario Infanta Leonor · ESInstituto de Salud Carlos III · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HIV infection is considered a scenario of accelerated aging. Previous studies have suggested a link between aging, frailty, and gut dysbiosis, but there is a knowledge gap regarding the HIV population. Our objective was to compare the fecal bacteriome of older people with HIV (PWH) and non-HIV controls, and to assess potential links between gut dysbiosis and frailty. A total of 36 fecal samples (24 from PWH and 12 from non-HIV controls) were submitted to a metataxonomic analysis targeting the V3-V4 hypervariable region of the 16S rRNA gene. High-quality reads were assembled and classified into operational taxonomic units. Alpha diversity, assessed using the Shannon index, was higher in the control group than in the HIV group (

Indexed as

agingdepressiondysbiosisfrailtygut microbiomeHIV

Identifiers

PMID37626801
PMCPMC10452058
OpenAlexW4386030452

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.