Evidence map›Paper›PMID 37627031›Full record

ArticleBiology2023

Effect of Mesenchymal Stem Cells Overexpressing BMP-9 Primed with Hypoxia on BMP Targets, Osteoblast Differentiation and Bone Repair.

Jessica Emanuella Rocha Moura Paz, Leticia Faustino Adolpho, Jaqueline Isadora Reis Ramos, Rayana Longo Bighetti-Trevisan, Robson Diego Calixto, Fabiola Singaretti Oliveira, Adriana Luisa Gonçalves Almeida, Marcio Mateus Beloti, Adalberto Luiz Rosa

Open access · goldAbstract read
In one paragraph

Article in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jessica Emanuella Rocha Moura PazBone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Ribeirão Preto 14040-904, SP, Brazil.
Leticia Faustino AdolphoBone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Ribeirão Preto 14040-904, SP, Brazil.ORCID 0000-0002-1952-5136
Jaqueline Isadora Reis RamosBone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Ribeirão Preto 14040-904, SP, Brazil.
Rayana Longo Bighetti-TrevisanBone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Ribeirão Preto 14040-904, SP, Brazil.
Robson Diego CalixtoBone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Ribeirão Preto 14040-904, SP, Brazil.
Fabiola Singaretti OliveiraBone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Ribeirão Preto 14040-904, SP, Brazil.
Adriana Luisa Gonçalves AlmeidaBone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Ribeirão Preto 14040-904, SP, Brazil.
Marcio Mateus BelotiBone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Ribeirão Preto 14040-904, SP, Brazil.ORCID 0000-0003-0149-7189
Adalberto Luiz RosaBone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Ribeirão Preto 14040-904, SP, Brazil.ORCID 0000-0002-6495-2778
Universidade de São Paulo · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior n/aNational Council for Scientific and Technological Development 307698/2021-1São Paulo Research Foundation 2017/12622-7
6 · The paper itself

Abstract

Bone formation is driven by many signaling molecules including bone morphogenetic protein 9 (BMP-9) and hypoxia-inducible factor 1-alpha (HIF-1α). We demonstrated that cell therapy using mesenchymal stem cells (MSCs) overexpressing BMP-9 (MSCs

Indexed as

BMP-9bonecell therapyHIF-1αhypoxiastem cells

Identifiers

PMID37627031
PMCPMC10452403
OpenAlexW4386030560

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.