Evidence map›Paper›PMID 37627099›Full record

ReviewCancers2023

Malignancy Associated with Low-Risk HPV6 and HPV11: A Systematic Review and Implications for Cancer Prevention.

Leandro Lima da Silva, Amanda Mara Teles, Joana M O Santos, Marcelo Souza de Andrade, Rui Medeiros, Ana I Faustino-Rocha, Paula A Oliveira, Ana Paula Azevedo Dos Santos, Fernanda Ferreira Lopes, Geraldo Braz and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 40 citations in OpenAlex.

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  11. Human Papillomavirus: An Old New History.Pathogens (Basel, Switzerland) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Leandro Lima da SilvaPost-Graduate Program in Adult Health (PPGSAD), Federal University of Maranhão (UFMA), São Luís 65080-805, MA, Brazil.
Amanda Mara TelesPost-Graduate Program in Adult Health (PPGSAD), Federal University of Maranhão (UFMA), São Luís 65080-805, MA, Brazil.
Joana M O SantosMolecular Oncology and Viral Pathology Group, Portuguese Institute of Oncology of Porto Research Center (CI-IPOP)/RISE@CI-IPOP (Health Research Network), Portuguese Institute of Oncology of Porto (IPO-Porto)/Porto Comprehensive Cancer Center (Porto.CCC), 4200-072 Porto, Portugal.ORCID 0000-0002-6268-524X
Marcelo Souza de AndradePost-Graduate Program in Adult Health (PPGSAD), Federal University of Maranhão (UFMA), São Luís 65080-805, MA, Brazil.
Rui MedeirosMolecular Oncology and Viral Pathology Group, Portuguese Institute of Oncology of Porto Research Center (CI-IPOP)/RISE@CI-IPOP (Health Research Network), Portuguese Institute of Oncology of Porto (IPO-Porto)/Porto Comprehensive Cancer Center (Porto.CCC), 4200-072 Porto, Portugal.ORCID 0000-0003-3010-8373
Ana I Faustino-RochaCentre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal.ORCID 0000-0001-5572-6317
Paula A OliveiraCentre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal.ORCID 0000-0001-9519-4044
Ana Paula Azevedo Dos SantosPost-Graduate Program in Adult Health (PPGSAD), Federal University of Maranhão (UFMA), São Luís 65080-805, MA, Brazil.
Fernanda Ferreira LopesPost-Graduate Program in Odontology, Federal University of Maranhão (UFMA), São Luís 65080-805, MA, Brazil.ORCID 0000-0001-5818-412X
Geraldo BrazPost-Graduate Program in Computing Sciences, Federal University of Maranhão (UFMA), São Luís 65080-805, MA, Brazil.ORCID 0000-0003-3731-6431
Haissa O BritoPost-Graduate Program in Adult Health (PPGSAD), Federal University of Maranhão (UFMA), São Luís 65080-805, MA, Brazil.
Rui M Gil da CostaPost-Graduate Program in Adult Health (PPGSAD), Federal University of Maranhão (UFMA), São Luís 65080-805, MA, Brazil.ORCID 0000-0002-2151-2449
Universidade Federal do Maranhão · BRUniversity of Trás-os-Montes and Alto Douro · PTInstituto Português de Oncologia Francisco Gentil · PTUniversidade Estadual do Maranhão · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior - finance code 001 and grant 13/2020 - PDPG Amazônia Legal 0810/2020/88881.510244/2020-01, by grant IECT-FAPEMA-05796/18 and FAPEMA IECT 30/2018 - IECT Saúde, grant PPSUS-02160/20 financed by FAPEMA, CNPq and the Brazilian Ministry of Health, by the ReseaFundação para a Ciência e Tecnologia LA/P/0045/2020 (ALiCE), UIDB/00511/2020 and UIDP/00511/2020 (LEPABE), funded by national funds through FCT/MCTES (PIDDAC), 2SMART (NORTE-01-0145-FEDER-000054)Fundação para a Ciência e Tecnologia projects UID/AGR/04033/2020, UIDB/CVT/00772/2020
6 · The paper itself

Abstract

High-risk human papillomavirus (HPV) is etiologically related to cervical cancer, other anogenital cancers and oropharyngeal carcinomas. Low-risk HPV, especially HPV6 and HPV11, cause genital warts and laryngeal papillomas. However, the accumulating data suggests that HPV6 and HPV11 may cause malignant lesions at non-cervical anatomic sites. This review aims to estimate the proportions of single and dual HPV6/11 infections in multiple cancers reported in the last 10 years in the Cochrane, Embasa and PubMed databases. Secondly, the genomes of HPV6/11 were compared with the most common high-risk genotype, HPV16, to determine the similarities and differences. A total of 11 articles were selected, including between one and 334 HPV+ cancer patients. The frequencies of single or dual HPV6/11 infections ranged between 0-5.5% for penile and 0-87.5% for laryngeal cancers and were null for vulvar, vaginal and oral cancers. The genomic similarities between HPV6/11 and HPV16 mainly involved the

Indexed as

low-risk HPVpapillomavirusretinoblastoma proteinsquamous cell carcinomavaccine

Identifiers

PMID37627099
PMCPMC10452364
OpenAlexW4385759481

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.