ReviewBiomolecules2023
Novel Imaging-Based Biomarkers for Identifying Carotid Plaque Vulnerability.
Review in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Imaging‑based models for predicting cerebrovascular complications of carotid stenosis.The Cochrane database of systematic reviews · 2026Pooled it
- Spatial-temporal and physical constrained deep learning model for simultaneous T1 and T2 reconstruction and mapping (STEP).Quantitative imaging in medicine and surgery · 2026Article
- Risk prediction and prevention in patients with advanced subclinical atherosclerosis.BMC cardiovascular disorders · 2026Review
- Distribution of high-resolution magnetic resonance imaging -based carotid Plaque-RADS subtypes among patients with acute cerebral infarction.Neuroradiology · 2026Article
- Residual cholesterol levels are associated with carotid plaque stability in patients with carotid stenosis.Scientific reports · 2026Article
- Association of Carotid Plaque Gray-scale Median with Plaque Size and Degree of Stenosis.Current medical imaging · 2026Article
- Assessment of perivascular adipose tissue attenuation using dual-layer spectral-detector CTA for identification of symptomatic carotid plaques.Japanese journal of radiology · 2025Article
- Artificial intelligence in carotid computed tomography angiography plaque detection: Decade of progress and future perspectives.World journal of radiology · 2025Review
- Lower Sphingomyelin SM 42:1 Plasma Level in Coronary Artery Disease-Preliminary Study.International journal of molecular sciences · 2025Article
- Article
- The Interplay Between Carotid Intima-Media Thickness and Selected Serum Biomarkers in Various Stages of Chronic Kidney Disease.Biomedicines · 2025Article
- Ultrasound Carotid Plaque Score and Severity of Coronary Artery Disease Assessed by Computed Tomography Angiography in Patients with Arterial Hypertension.Diagnostics (Basel, Switzerland) · 2024Article
- Interleukin-6 and thyroid-stimulating hormone index predict plaque stability in carotid artery stenosis: analyses by lasso-logistic regression.Frontiers in cardiovascular medicine · 2024Article
- The Relation of the Iron Metabolism Index to the Vulnerability Index of Carotid Plaque with Different Degrees of Stenosis.Diagnostics (Basel, Switzerland) · 2023Article
- Controversies in the management of asymptomatic carotid stenosis: from best medical therapy to a redefinition of surgical indications.Frontiers in neurologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carotid artery disease has traditionally been assessed based on the degree of luminal narrowing. However, this approach, which solely relies on carotid stenosis, is currently being questioned with regard to modern risk stratification approaches. Recent guidelines have introduced the concept of the "vulnerable plaque," emphasizing specific features such as thin fibrous caps, large lipid cores, intraplaque hemorrhage, plaque rupture, macrophage infiltration, and neovascularization. In this context, imaging-based biomarkers have emerged as valuable tools for identifying higher-risk patients. Non-invasive imaging modalities and intravascular techniques, including ultrasound, computed tomography, magnetic resonance imaging, intravascular ultrasound, optical coherence tomography, and near-infrared spectroscopy, have played pivotal roles in characterizing and detecting unstable carotid plaques. The aim of this review is to provide an overview of the evolving understanding of carotid artery disease and highlight the significance of imaging techniques in assessing plaque vulnerability and informing clinical decision-making.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.