Evidence map›Paper›PMID 37627622›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Biomarkers of Oxidative Stress in Systemic Lupus Erythematosus Patients with Active Nephritis.

Lu Liu, Karina de Leeuw, Suzanne Arends, Berber Doornbos-van der Meer, Marian L C Bulthuis, Harry van Goor, Johanna Westra, Dutch LN Studies

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lu LiuDepartment of Rheumatology and Clinical Immunology, University Medical Centre Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0001-9274-1372
Karina de LeeuwDepartment of Rheumatology and Clinical Immunology, University Medical Centre Groningen, 9713 GZ Groningen, The Netherlands.
Suzanne ArendsDepartment of Rheumatology and Clinical Immunology, University Medical Centre Groningen, 9713 GZ Groningen, The Netherlands.
Berber Doornbos-van der MeerDepartment of Rheumatology and Clinical Immunology, University Medical Centre Groningen, 9713 GZ Groningen, The Netherlands.
Marian L C BulthuisDepartment of Pathology and Medical Biology, University Medical Centre Groningen, 9713 GZ Groningen, The Netherlands.
Harry van GoorDepartment of Pathology and Medical Biology, University Medical Centre Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0002-6670-1577
Johanna WestraDepartment of Rheumatology and Clinical Immunology, University Medical Centre Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0002-6581-6508
Dutch LN Studies
University Medical Center Groningen · NL

Funding

Chinese Scholarship Council 202006170049De Cock-Hadders Foundation 2022-17
6 · The paper itself

Abstract

Oxidative stress plays an important role in systemic lupus erythematosus (SLE) and especially in lupus nephritis (LN). The aim of this study was to compare redox-related biomarkers between patients with active LN, quiescent SLE (Q-SLE) and healthy controls (HC) and to explore their association with clinical characteristics such as disease activity in patients. We investigated levels of plasma free thiols (R-SH, sulfhydryl groups), levels of soluble receptor for advanced glycation end products (sRAGE) and levels of malondialdehyde (MDA) in SLE patients with active LN (

Indexed as

free thiolsmalondialdehyde (MDA)reactive oxygen species (ROS)soluble receptor for advanced glycation end products (sRAGE)

Identifiers

PMID37627622
PMCPMC10451241
OpenAlexW4385955495

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.