Evidence map›Paper›PMID 37629366›Full record

ArticleJournal of clinical medicine2023

Association of TNF-α (-308G/A) Gene Polymorphism with Changes in Circulating TNF-α Levels in Response to CPAP Treatment in Adults with Coronary Artery Disease and Obstructive Sleep Apnea.

Yeliz Celik, Yüksel Peker, Tülay Yucel-Lindberg, Tilia Thelander, Afrouz Behboudi

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00519597 (Randomized Intervention With CPAP in Coronary Artery Disease and Sleep Apnea - RICCADSA Trial), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00519597 phase4completednot on this map

Randomized Intervention With CPAP in Coronary Artery Disease and Sleep Apnea - RICCADSA Trial

TypeinterventionalSponsorSkaraborg HospitalRan2005 to 2013Enrolled511ConditionsCoronary Artery Disease, Obstructive Sleep ApneaArmsResMed S8 (Auto-CPAP)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Yeliz CelikDepartment of Pulmonary Medicine, Koc University School of Medicine, and Koc University Research Center for Translational Medicine (KUTTAM), Koc University, 34010 Istanbul, Turkey.
Yüksel PekerDepartment of Pulmonary Medicine, Koc University School of Medicine, and Koc University Research Center for Translational Medicine (KUTTAM), Koc University, 34010 Istanbul, Turkey.ORCID 0000-0001-9067-6538
Tülay Yucel-LindbergDepartment of Dental Medicine, Karolinska Institute, 17177 Stockholm, Sweden.ORCID 0000-0003-0129-8809
Tilia ThelanderDivision of Biomedicine, School of Heath Sciences, University of Skövde, 54128 Skövde, Sweden.
Afrouz BehboudiDivision of Biomedicine, School of Heath Sciences, University of Skövde, 54128 Skövde, Sweden.ORCID 0000-0003-2525-3752
University of Skövde · SEBrigham and Women's Hospital · USKarolinska Institutet · SEKoç University · TR

Funding

ResMed Foundation, USA N/A
6 · The paper itself

Abstract

rationaleWe recently demonstrated that patients with coronary artery disease (CAD) and obstructive sleep apnea (OSA) carrying the tumor necrosis factor-alpha

methodsThis study was a secondary analysis of the RICCADSA trial (NCT00519597) conducted in Sweden. CAD patients with OSA (apnea-hypopnea index) of ≥15 events/h and an Epworth Sleepiness Scale (ESS) score of <10 were randomized to CPAP or no-CPAP groups, and OSA patients with an ESS score of ≥10 were offered CPAP treatment. Blood samples were obtained at baseline and 12-month follow-up visits.

resultsIn all, 239 participants (206 men and 33 women; mean age 64.9 (SD 7.7) years) with polymorphism data and circulating levels of

conclusionsOur results suggest that

Indexed as

coronary artery diseaseobstructive sleep apneatumor necrosis factor

Identifiers

PMID37629366
PMCPMC10455347
OpenAlexW4385878499

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.