Evidence mapPaperPMID 37629496Full record

ReviewLife (Basel, Switzerland)2023

Novel Biomarkers for Atherosclerotic Disease: Advances in Cardiovascular Risk Assessment.

Raul-Alexandru Jigoranu, Mihai Roca, Alexandru-Dan Costache, Ovidiu Mitu, Alexandru-Florinel Oancea, Radu-Stefan Miftode, Mihai Ștefan Cristian Haba, Eosefina Gina Botnariu, Alexandra Maștaleru, Radu-Sebastian Gavril and 6 more

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Raul-Alexandru JigoranuDepartment of Medical Specialties I, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.
Mihai RocaDepartment of Medical Specialties I, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.
Alexandru-Dan CostacheDepartment of Medical Specialties I, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.ORCID 0000-0001-8544-9904
Ovidiu MituDepartment of Medical Specialties I, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.ORCID 0000-0002-9438-8565
Alexandru-Florinel OanceaDepartment of Medical Specialties I, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.ORCID 0000-0002-5249-4562
Radu-Stefan MiftodeDepartment of Medical Specialties I, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.ORCID 0000-0002-2610-6482
Mihai Ștefan Cristian HabaDepartment of Medical Specialties I, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.
Eosefina Gina BotnariuDepartment of Internal Medicine II, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.ORCID 0000-0001-8964-1127
Alexandra MaștaleruDepartment of Medical Specialties I, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.ORCID 0000-0002-0008-9696
Radu-Sebastian GavrilDepartment of Medical Specialties I, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.ORCID 0000-0002-6406-6573
Bogdan-Andrei TrandabatDepartment of Surgery II, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.
Sabina Ioana ChiricaFaculty of General Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.
Raluca Maria HabaFaculty of General Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.ORCID 0000-0003-1955-3521
Maria Magdalena LeonDepartment of Medical Specialties I, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.
Irina-Iuliana CostacheDepartment of Medical Specialties I, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.
Florin MituDepartment of Medical Specialties I, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.ORCID 0000-0003-1801-9327

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is a significant health concern with a growing incidence worldwide. It is directly linked to an increased cardiovascular risk and to major adverse cardiovascular events, such as acute coronary syndromes. In this review, we try to assess the potential diagnostic role of biomarkers in the early identification of patients susceptible to the development of atherosclerosis and other adverse cardiovascular events. We have collected publications concerning already established parameters, such as low-density lipoprotein cholesterol (LDL-C), as well as newer markers, e.g., apolipoprotein B (apoB) and the ratio between apoB and apoA. Additionally, given the inflammatory nature of the development of atherosclerosis, high-sensitivity c-reactive protein (hs-CRP) or interleukin-6 (IL-6) are also discussed. Additionally, newer publications on other emerging components linked to atherosclerosis were considered in the context of patient evaluation. Apart from the already in-use markers (e.g., LDL-C), emerging research highlights the potential of newer molecules in optimizing the diagnosis of atherosclerotic disease in earlier stages. After further studies, they might be fully implemented in the screening protocols.

Indexed as

apolipoprotein Batherosclerosisinterleukin-6

Identifiers

PMID37629496
PMCPMC10455542

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.