Evidence map›Paper›PMID 37629751›Full record

ReviewMedicina (Kaunas, Lithuania)2023

Role of Circular RNAs in Atherosclerosis through Regulation of Inflammation, Cell Proliferation, Migration, and Apoptosis: Focus on Atherosclerotic Cerebrovascular Disease.

Zheng Zhang, Lingfei Li, Huanqing Shi, Biao Chen, Xiaoqin Li, Yuyao Zhang, Fei Liu, Wan Wei, Yongji Zhou, Keqin Liu and 7 more

Open access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. [circ_0084043/miR-31-5p Is Involved in Atherosclerosis by Regulating HMGA1: Investigation of the Mechanisms].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Zheng ZhangThe Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Lingfei LiDepartment of Neurology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Huanqing ShiThe Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Biao ChenThe Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Xiaoqin LiThe Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Yuyao ZhangThe Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Fei LiuDepartment of Neurology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Wan WeiDepartment of Neurology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Yongji ZhouDepartment of Neurology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Keqin LiuDepartment of Neurology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Wenqing XiaDepartment of Neurology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Xin GuThe Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Jinyu HuangDepartment of Cardiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
Sheng TuState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310006, China.
Congguo YinThe Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Anwen ShaoDepartment of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China.
Lin JiangThe Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Zhejiang Chinese Medical University · CNHangzhou First People's Hospital · CNSecond Affiliated Hospital of Zhejiang University · CNState Key Laboratory of Diagnosis and Treatment of Infectious Diseases

Funding

Hangzhou Health Science and Technology Project ZD20200056, ZD20210007, and A20200341National Key R&D Program of China 2021YFC2301800,2022YFC2304500Zhejiang Basic Public Welfare Research Program LGF20H090008 and GC22H095676
6 · The paper itself

Abstract

Atherosclerosis (AS) is a disease dangerous to human health and the main pathological cause of ischemic cardiovascular diseases. Although its pathogenesis is not fully understood, numerous basic and clinical studies have shown that AS is a chronic inflammatory disease existing in all stages of atherogenesis. It may be a common link or pathway in the pathogenesis of multiple atherogenic factors. Inflammation is associated with AS complications, such as plaque rupture and ischemic cerebral infarction. In addition to inflammation, apoptosis plays an important role in AS. Apoptosis is a type of programmed cell death, and different apoptotic cells have different or even opposite roles in the process of AS. Unlike linear RNA, circular RNA (circRNA) a covalently closed circular non-coding RNA, is stable and can sponge miRNA, which can affect the stages of AS by regulating downstream pathways. Ultimately, circRNAs play very important roles in AS by regulating inflammation, apoptosis, and some other mechanisms. The study of circular RNAs can provide new ideas for the prediction, prevention, and treatment of AS.

Indexed as

AtherosclerosisCerebrovascular DisordersMicroRNAsApoptosisCell ProliferationHumansInflammationRNA, CircularMicroRNAsRNA, Circularatherosclerosiscell apoptosiscell migrationcell proliferationcircular RNA (circRNA)inflammation

Identifiers

PMID37629751
PMCPMC10456328
OpenAlexW4385805391

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.