Evidence map›Paper›PMID 37630578›Full record

ReviewMicroorganisms2023

Current Insights into the Use of Probiotics and Fatty Acids in Alleviating Depression.

Han Gao, Chengwei He, Shuzi Xin, Rongxuan Hua, Yixuan Du, Boya Wang, Fengrong Gong, Xinyi Yu, Luming Pan, Lei Gao and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Human Gut Microbiota for Diagnosis and Treatment of Depression.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Han GaoDepartment of Clinical Laboratory, Aerospace Center Hospital, Beijing 100049, China.
Chengwei HeDepartment of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.ORCID 0000-0002-7215-053X
Shuzi XinDepartment of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.
Rongxuan HuaDepartment of Clinical Medicine, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.
Yixuan DuDepartment of Clinical Medicine, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.
Boya WangDepartment of Digestive Oncology, Peking University Cancer Hospital, Beijing 100044, China.
Fengrong GongDepartment of Clinical Medicine, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.
Xinyi YuDepartment of Clinical Medicine, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.
Luming PanDepartment of Clinical Medicine, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.
Lei GaoDepartment of Biomedical Informatics, School of Biomedical Engineering, Capital Medical University, Beijing 100069, China.ORCID 0000-0003-0944-3871
Jingdong XuDepartment of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.ORCID 0000-0003-4546-563X
Capital Medical University · CNPeking University · CN

Funding

National Natural Science Foundation of China 82174056
6 · The paper itself

Abstract

(1) Background: Depression is the most prevalent psychiatric symptom present among individuals of all ages and backgrounds, impacting an estimated 300 million people globally. Therefore, it demands a significant amount of attention when it comes to managing depression. A growing amount of data reveal that probiotics and fatty acids could be beneficial to depression. However, the opposing position maintains that they have no influence on depression. A network meta-analyses of existing datasets aid in the estimation of comparative efficacy as well as in achieving an understanding of the relative merits of different therapies. The purpose of this study was to investigate the current evidence for probiotic or fatty acid depression therapy and to establish a practical alternative for depression patients using a meta-analysis and metagenomic data from a Wistar-Kyoto (WKY) depressed rat model. (2) Methods: Probiotic data were obtained from seven randomized controlled trial studies (

Indexed as

depressionfatty acidsgut microbiomemeta-analysisprobioticsRCT

Identifiers

PMID37630578
PMCPMC10459535
OpenAlexW4385603088

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.