Evidence map›Paper›PMID 37630723›Full record

ArticleNutrients2023

Ado-Mediated Depletion of Taurine Impairs Mitochondrial Respiratory Capacity and Alters the Chromatin Landscape of Inguinal Adipose Tissue.

Pei-Yin Tsai, Bo Shui, Seoyeon Lee, Yang Liu, Yue Qu, Chloe Cheng, Kaydine Edwards, Callie Wong, Ryan Meng-Killeen, Paul D Soloway and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Pei-Yin TsaiDivision of Nutritional Sciences, Cornell University, Ithaca, NY 14850, USA.ORCID 0000-0001-7132-5986
Bo ShuiDepartment of Biomedical Sciences, Cornell University, Ithaca, NY 14850, USA.
Seoyeon LeeDivision of Nutritional Sciences, Cornell University, Ithaca, NY 14850, USA.
Yang LiuDivision of Nutritional Sciences, Cornell University, Ithaca, NY 14850, USA.ORCID 0000-0003-2933-6088
Yue QuDivision of Nutritional Sciences, Cornell University, Ithaca, NY 14850, USA.ORCID 0000-0002-2593-3654
Chloe ChengDepartment of Biomedical Sciences, Cornell University, Ithaca, NY 14850, USA.
Kaydine EdwardsDivision of Nutritional Sciences, Cornell University, Ithaca, NY 14850, USA.
Callie WongDivision of Nutritional Sciences, Cornell University, Ithaca, NY 14850, USA.
Ryan Meng-KilleenDivision of Nutritional Sciences, Cornell University, Ithaca, NY 14850, USA.
Paul D SolowayDivision of Nutritional Sciences, Cornell University, Ithaca, NY 14850, USA.ORCID 0000-0003-1967-0437
Joeva J BarrowDivision of Nutritional Sciences, Cornell University, Ithaca, NY 14850, USA.ORCID 0000-0002-2930-2550
Cornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-shivering thermogenesis (NST) has strong potential to combat obesity; however, a safe molecular approach to activate this process has not yet been identified. The sulfur amino acid taurine has the ability to safely activate NST and confer protection against obesity and metabolic disease in both mice and humans, but the mechanism of this action is unknown. In this study, we discover that a suite of taurine biosynthetic enzymes, especially that of cysteamine dioxygenase (ADO), significantly increases in response to β

Indexed as

Adipose TissueChromatinAdipocytesAnimalsHumansMiceRespirationRespiratory RateChromatinadipocytescysteamine dioxygenasemitochondrial respirationnon-shivering thermogenesisobesitytaurine

Identifiers

PMID37630723
PMCPMC10458711
OpenAlexW4385760534

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.