Evidence map›Paper›PMID 37630972›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Neuroprotective Effects of Tryptanthrin-6-Oxime in a Rat Model of Transient Focal Cerebral Ischemia.

Mark B Plotnikov, Galina A Chernysheva, Vera I Smol'yakova, Oleg I Aliev, Anna M Anishchenko, Olga A Ulyakhina, Eugene S Trofimova, Anastasia A Ligacheva, Nina D Anfinogenova, Anton N Osipenko and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Chemistry and Biological Activity of 11Molecules (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Mark B PlotnikovDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634028, Russia.ORCID 0000-0002-0548-6586
Galina A ChernyshevaDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634028, Russia.
Vera I Smol'yakovaDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634028, Russia.
Oleg I AlievDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634028, Russia.
Anna M AnishchenkoDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634028, Russia.
Olga A UlyakhinaDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634028, Russia.
Eugene S TrofimovaDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634028, Russia.
Anastasia A LigachevaDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634028, Russia.
Nina D AnfinogenovaCardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634012, Russia.ORCID 0000-0003-1106-0730
Anton N OsipenkoDepartment of Pharmacology, Siberian State Medical University, Tomsk 634050, Russia.ORCID 0000-0002-4763-3214
Anastasia R KovrizhinaKizhner Research Center, Tomsk Polytechnic University, Tomsk 634050, Russia.ORCID 0000-0002-9316-0964
Andrei I KhlebnikovKizhner Research Center, Tomsk Polytechnic University, Tomsk 634050, Russia.ORCID 0000-0002-3022-4510
Igor A SchepetkinDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA.
Anastasia G DrozdResearch School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk 634050, Russia.ORCID 0000-0003-0633-213X
Evgenii V PlotnikovResearch School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk 634050, Russia.ORCID 0000-0002-4374-6422
Dmitriy N AtochinCardiovascular Research Center, Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02115, USA.
Mark T QuinnDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA.ORCID 0000-0001-8114-5073
Russian Academy of Sciences · RUNational Research Tomsk State University · RUMontana State University · USHarvard University · USSiberian State Medical University · RU

Funding

Russian Science Foundation 23-25-00174
6 · The paper itself

Abstract

The activation of

Indexed as

anti-inflammatory activityantioxidant activityc-Jun N-terminal kinasefocal cerebral ischemiaischemic strokeneuroprotective activitytryptanthrin-6-oxime

Identifiers

PMID37630972
PMCPMC10457995
OpenAlexW4385318162

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.