Evidence map›Paper›PMID 37636994›Full record

ArticleOpen medicine (Warsaw, Poland)2023

Effect of RUNX1/FOXP3 axis on apoptosis of T and B lymphocytes and immunosuppression in sepsis.

Yangfa Chao, Wenting Huang, Zhiheng Xu, Ping Li, Shaodong Gu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open medicine (Warsaw, Poland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yangfa ChaoDepartment of Surgical Area 4, Shenzhen Bao'an Traditional Chinese Medicine Hospital Group, Shenzhen, Guangdong Province, 518000, China.
Wenting HuangDepartment of Acupuncture, Luohu District Chronic Disease Prevention and Treatment Hospital, Shenzhen, China.
Zhiheng XuThe Second Department of Surgery, The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou, China.
Ping LiDepartment of Surgical Area 4, Shenzhen Bao'an Traditional Chinese Medicine Hospital Group, Shenzhen, Guangdong Province, 518000, China.
Shaodong GuDepartment of Surgical Area 4, Shenzhen Bao'an Traditional Chinese Medicine Hospital Group, No. 25 Yu'an 2nd Road, Bao'an District, Shenzhen, Guangdong Province, 518000, China.
First Affiliated Hospital of Guangzhou University of Chinese Medicine · CNShenzhen Bao'an District People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphocyte apoptosis is a latent factor for immunosuppression in sepsis. Forkhead box protein P3 (FOXP3) can interact with RUNX family transcription factor 1 (RUNX1) in regulatory T cells. Our research was to probe whether RUNX1/FOXP3 axis affects immunosuppression in the process of sepsis by modulating T and B lymphocyte apoptosis. We constructed sepsis model in mice and mouse CD4

Indexed as

apoptosisFOXP3lymphocytesRUNX1sepsis

Identifiers

PMID37636994
PMCPMC10448307
OpenAlexW4386144415

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.