ArticleAnnals of surgery open : perspectives of surgical history, education, and clinical approaches2021
Preoperative Depression and Anxiety Impact on Inpatient Surgery Outcomes: A Prospective Cohort Study.
Article in Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 5 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Patient-related risk factors for new persistent opioid use after surgery among opioid-naïve individuals in the United States: a systematic review and meta-analysis.Pain medicine (Malden, Mass.) · 2026Pooled it
- The effect of preoperative mental health on outcomes of cervical spine surgery: A systematic review and meta-analysis.Neurosurgical review · 2026Pooled it
- Prehabilitation including psychological interventions reduces overall postoperative complications following cancer surgery: a systematic review and meta-analysis of randomised controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- The impact of compassion-based interventions on perioperative anxiety and depression: A systematic review and meta-analysis.Journal of affective disorders · 2024Pooled it
- Global prevalence and factors associated with preoperative depression in women undergoing breast surgery: a meta-analysis and meta-regression.Breast cancer research and treatment · 2024Pooled it
- The Effect of Low-Dose Dexmedetomidine Nasal Spray on Anxiety Levels in Gynaecological Patients on the Day of Surgery: A Randomised Controlled Study.Drug design, development and therapy · 2026Trial
- Preoperative quality of life in patients undergoing liver surgery.Surgery open science · 2026Article
- Article
- Relationship Between Postoperative Pain in Surgery and the Onset of Psychological Symptoms Such as Mental Anxiety and Depression.Actas espanolas de psiquiatria · 2026Article
- Increasing Use of Wearable Devices for Health or Activity Tracking Among Adults with Chronic Diseases in the US.Journal of the American College of Surgeons · 2026Article
- Outcomes Following Regenerative Peripheral Nerve Interface Surgery and Associations With Preoperative Mental Health: A Retrospective Analysis of Upper-Extremity Neuromas.Journal of hand surgery global online · 2026Article
- Nationwide Real-World Modeling of Surgical Outcomes in Elderly Patients: Incorporating Geriatric-Specific Risk Factors Into Prediction of Mortality and Morbidity.Annals of gastroenterological surgery · 2026Article
- Psychological Resilience in Surgery: Psychobiological Pathways, Clinical Impact, and Perioperative Modulation-A Narrative Review.Journal of personalized medicine · 2026Review
- Association Between Depression and Increased Odds of Inpatient Mortality Following Hip Fracture Repair.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026Article
- Outcomes of Patients With Schizophrenia and Bipolar Disorder Undergoing Lumbar Fusion: A Retrospective National Database Study.International journal of spine surgery · 2026Article
- Targeting neuroinflammation and PVNMaterials today. Bio · 2026Article
- Observational
- Article
- Review
- Decoding Fear: Analysis and Prognosis of Preoperatory Stress Level Through Advanced Statistical Modelling-A Prospective Study Across Multiple Surgical Specialties.Medical sciences (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To determine the association of preoperative mood symptoms and postoperative adverse outcomes; to explore sex-specific differences. Background: Depression and anxiety can increase postoperative mortality. Psychological stress is associated with a chronic inflammatory response unfavorable to postsurgical healing. Methods: Prospective cohort study. Patients were recruited from surgical preadmission clinics at a university hospital. Preoperative depression and anxiety were measured via the Beck Depression and Beck Anxiety Inventories (BDI-II and BAI). Our primary outcome was a composite of postoperative complications, extended length of stay (ELOS) and early readmission. Associated variables included demographics, preoperative pain, pain tolerance/catastrophizing, coping mechanisms, postoperative pain, and opioid use. We adjusted for age, comorbidities, and surgical specialty. Results: Of 1061 recruited patients (ten surgical specialties, 2015-2020), 455 males and 486 females had preoperative and postoperative data available. Mean age was 62.9 (range 20.2-96.2). At baseline, 9.3% of patients had moderate or severe depression; 7.4% had moderate or severe anxiety. Females were more likely to be moderately or severely depressed (11% vs 7%, Conclusion: Preoperative depression and anxiety negatively impact surgical outcomes in female patients undergoing major surgery.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.