Evidence map›Paper›PMID 37639334›Full record

ArticleClinical and translational science2023

Co-consuming green tea with raloxifene decreases raloxifene systemic exposure in healthy adult participants.

John D Clarke, Sabrina M Judson, Dan-Dan Tian, Trevor O Kirby, Rakshit S Tanna, Adrienn Matula-Péntek, Miklós Horváth, Matthew E Layton, John R White, Nadja B Cech and 4 more

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

John D ClarkeDepartment of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington, USA.
Sabrina M JudsonDepartment of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington, USA.
Dan-Dan TianDepartment of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington, USA.
Trevor O KirbyDepartment of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington, USA.
Rakshit S TannaDepartment of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington, USA.
Adrienn Matula-PéntekSOLVO Biotechnology, Szeged, Hungary.
Miklós HorváthSOLVO Biotechnology, Szeged, Hungary.
Matthew E LaytonElson S. Floyd College of Medicine, Washington State University, Spokane, Washington, USA.ORCID 0000-0002-3287-9203
John R WhiteDepartment of Pharmacotherapy, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington, USA.
Nadja B CechDepartment of Chemistry and Biochemistry, University of North Carolina Greensboro, Greensboro, North Carolina, USA.
Kenneth E ThummelCenter of Excellence for Natural Product Drug Interaction Research, Spokane, Washington, USA.
Jeannine S McCuneCenter of Excellence for Natural Product Drug Interaction Research, Spokane, Washington, USA.ORCID 0000-0002-0795-497X
Danny D ShenCenter of Excellence for Natural Product Drug Interaction Research, Spokane, Washington, USA.
Mary F PaineDepartment of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington, USA.ORCID 0000-0002-3331-1839
Washington State University Spokane · USSolvo Biotechnology (Hungary) · HUUniversity of Washington · USCity of Hope · USUniversity of North Carolina at Greensboro · US

Funding

Pharmacology CoreU54AT008909 · NCCIH · WASHINGTON STATE UNIVERSITY · PI PAINE, MARY F · 2015 to 2024
$22.4M
NCCIH NIH HHS U54 AT008909
6 · The paper itself

Abstract

Green tea is a popular beverage worldwide. The abundant green tea catechin (-)-epigallocatechin gallate (EGCG) is a potent in vitro inhibitor of intestinal UDP-glucuronosyltransferase (UGT) activity (K

Indexed as

CatechinTeaAdultCross-Over StudiesDrug InteractionsGlucuronidesHumansRaloxifene HydrochlorideCatechinGlucuronidesRaloxifene HydrochlorideTea

Identifiers

PMID37639334
PMCPMC10582660
OpenAlexW4386216062

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.