Evidence map›Paper›PMID 37640847›Full record

ArticleScientific reports2023

Remote psychophysical testing of smell in patients with persistent olfactory dysfunction after COVID-19.

Marcela Martončíková, Pavel Doležal, Kamila Fabianová, Miloslav Karhánek, Ján Gálik, Adam Raček, Alexandra Popovičová, Enikő Račeková

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marcela MartončíkováInstitute of Neurobiology, Biomedical Research Center, Slovak Academy of Sciences, Šoltésovej 4, 040 01, Košice, Slovakia.ORCID http://orcid.org/0000-0001-5418-1693
Pavel DoležalDepartment of Otorhinolaryngology and Head and Neck Surgery, University Hospital-St. Michal's Hospital, Slovak Medical University, Bratislava, Slovakia.ORCID http://orcid.org/0000-0002-5467-6271
Kamila FabianováInstitute of Neurobiology, Biomedical Research Center, Slovak Academy of Sciences, Šoltésovej 4, 040 01, Košice, Slovakia.ORCID http://orcid.org/0000-0003-2965-4625
Miloslav KarhánekLaboratory of Bioinformatics, Biomedical Research Center, Slovak Academy of Sciences, Dúbravská Cesta 9, 845 05, Bratislava, Slovakia.ORCID http://orcid.org/0000-0001-8310-681X
Ján GálikInstitute of Neurobiology, Biomedical Research Center, Slovak Academy of Sciences, Šoltésovej 4, 040 01, Košice, Slovakia.ORCID http://orcid.org/0000-0001-9581-9585
Adam RačekInstitute of Neurobiology, Biomedical Research Center, Slovak Academy of Sciences, Šoltésovej 4, 040 01, Košice, Slovakia.ORCID http://orcid.org/0000-0001-9729-1921
Alexandra PopovičováInstitute of Neurobiology, Biomedical Research Center, Slovak Academy of Sciences, Šoltésovej 4, 040 01, Košice, Slovakia.ORCID http://orcid.org/0000-0002-7137-0960
Enikő RačekováInstitute of Neurobiology, Biomedical Research Center, Slovak Academy of Sciences, Šoltésovej 4, 040 01, Košice, Slovakia. racekova@saske.sk.ORCID http://orcid.org/0000-0002-3650-2251

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Olfactory dysfunction associated with coronavirus 2 (SARS-CoV-2) infection is in most cases transient, recovering spontaneously within a few days. However, in some patients it persists for a long time, affects their everyday life and endangers their health. Hence, we focused on patients with persistent loss of smell. The aim of this study was to evaluate olfactory dysfunction using a standardized test. Due to the pandemic, olfactory testing was performed online. Smell tests (Odorized Markers Test, OMT) were sent home to the patients. Together with the smell self-testing, participants reported and assessed several parameters (age, sex, subjective assessment of smell and taste, nasal patency, etc.) in an online questionnaire. Based on the questionnaire outcomes, the results were sent to the patients along with a list of participating otolaryngologists who provided them with professional care. From March to June 2021, 1025 patients requested smell testing, of these, 824 met the inclusion criteria of this study. The duration of the olfactory dysfunction at the time of testing ranged from 1 month to 1 year. Using the OMT, impaired smell ability-anosmia or hyposmia-was confirmed in 82.6% of participants. A total of 17.4% of participants were determined to be normosmic however, more than 50% of them complained of parosmia and/or phantosmia. Our study demonstrates the relevance of psychophysical smell testing and its suitability for remote use during the pandemic. This study also revealed several correlations between prolonged olfactory dysfunction and the monitored parameters.

Indexed as

COVID-19Olfaction DisordersAnosmiaHumansSARS-CoV-2Smell

Identifiers

PMID37640847
PMCPMC10462624

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.