Evidence map›Paper›PMID 37645775›Full record

ArticlebioRxiv : the preprint server for biology2024

ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6 specific nanobody restricts M. tuberculosis growth in macrophages.

Timothy A Bates, Mila Trank-Greene, Xammy Nguyenla, Aidan Anastas, Sintayehu K Gurmessa, Ilaria R Merutka, Shandee D Dixon, Anthony Shumate, Abigail R Groncki, Matthew Ah Parson and 6 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Timothy A BatesDepartment of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, Oregon, United States.ORCID 0000-0002-2533-7668
Mila Trank-GreeneDepartment of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, Oregon, United States.ORCID 0009-0000-4934-3811
Xammy NguyenlaDepartment of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, Oregon, United States.ORCID 0000-0002-7532-8356
Aidan AnastasDepartment of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, Oregon, United States.ORCID 0009-0005-3875-1162
Sintayehu K GurmessaDepartment of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, Oregon, United States.ORCID 0000-0003-1644-2359
Ilaria R MerutkaDepartment of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, Oregon, United States.ORCID 0000-0003-0612-7400
Shandee D DixonDepartment of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, Oregon, United States.ORCID 0000-0002-6013-0080
Anthony ShumateDepartment of Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, Oregon, United States.ORCID 0000-0002-8180-9893
Abigail R GronckiDepartment of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, Oregon, United States.
Matthew Ah ParsonDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, Canada.ORCID 0000-0001-6270-559X
Jessica R IngramProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States.ORCID 0000-0003-1294-0270
Eric BarklisDepartment of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, Oregon, United States.ORCID 0000-0003-4944-6671
John E BurkeDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, Canada.ORCID 0000-0001-7904-9859
Ujwal ShindeDepartment of Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, Oregon, United States.ORCID 0000-0001-6229-2609
Hidde L PloeghProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States.ORCID 0000-0002-1090-6071
Fikadu G TafesseDepartment of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, Oregon, United States.ORCID 0000-0002-8575-4164
Oregon Health & Science University · USBoston Children's Hospital · USUniversity of British Columbia · CAUniversity of Victoria · CA

Funding

Multidisciplinary Research Training in Pulmonary MedicineT32HL083808 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M., SLATORE, CHRISTOPHER G. · 2008 to 2025
$5.3M
HIV-1 Gag Precursor Protein InteractionsR01AI152579 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI BARKLIS, ERIC W · 2020 to 2024
$2.5M
Determining the role of sphingolipids in Mycobacterium tuberculosis infectionR01AI141549 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI TAFESSE, FIKADU G. · 2020 to 2025
$2.4M
Octet Red384S10OD023413 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI BARR-GILLESPIE, PETER GORDON · 2017 to 2017
$318k
NHLBI NIH HHS T32 HL083808NIAID NIH HHS R01 AI141549NIAID NIH HHS R01 AI152579NIH HHS S10 OD023413
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID37645775
PMCPMC10462100
OpenAlexW4385984456

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.