Evidence mapPaperPMID 37645820Full record

ArticlebioRxiv : the preprint server for biology2023

Differences in the Pupillary Responses to Evening Light between Children and Adolescents.

Lauren E Hartstein, Monique K LeBourgeois, Mark T Durniak, Raymond P Najjar

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Lauren E HartsteinDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA.
Monique K LeBourgeoisDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA.
Mark T DurniakExcelitas Technologies, Boulder, CO, USA.
Raymond P NajjarCenter for Innovation & Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
University of Colorado Boulder · USExcelitas Technologies (United States) · USNational University of Singapore · SG

Funding

Transdisciplinary Training in Sleep and Circadian ResearchT32HL149646 · UNIVERSITY OF COLORADO · 2025 to 2025
$341k
NHLBI NIH HHS T32 HL149646NICHD NIH HHS R01 HD087707
6 · The paper itself

Abstract

Purpose: To assess differences in the pupillary light responses (PLRs) to blue and red evening lights between children and adolescents. Methods: Forty healthy participants (8-9 years, n=21; 15-16 years, n=19) completed a PLR assessment 1 h before their habitual bedtime. After a 1 h dim-light adaptation period (<1 lux), baseline pupil diameter was measured in darkness for 30 s, followed by a 10 s exposure to 3.0×10 Results: Across both age groups, maximum pupil constriction was significantly greater (p< 0.001, η Conclusions: Blue light elicited a greater and more sustained pupillary response than red light across participants. However, the overall amplitude of the rod/cone-driven phasic response was greater in children than in adolescents. Our findings using the PLR highlight a higher sensitivity to evening light in children compared to adolescents, and continued maturation of the human non-visual photoreception/system throughout development.

Indexed as

adolescentschildrenintrinsically photosensitive retinal ganglion cellslight exposurepupillary light reflex

Identifiers

PMID37645820
PMCPMC10461909
OpenAlexW4385811623

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.