ArticleThe Journal of nutrition2023
Dietary Vitamin A Affects the Function of Incretin-Producing Enteroendocrine Cells in Male Mice Fed a High-Fat Diet.
Rossana M Calderon, Marcin Golczak, Jisun Paik, William S Blaner
Open access · greenAbstract read
In one paragraphArticle in The Journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 2 citations in OpenAlex.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
4 authors at 4 institutions in 1 country.
Rossana M CalderonDepartment of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, United States. Electronic address: rmc2204@cumc.columbia.edu.
Marcin GolczakDepartment of Pharmacology, Case Western Reserve University, Cleveland, OH, United States; Cleveland Center for Membrane and Structural Biology, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Jisun PaikDepartment of Comparative Medicine, University of Washington, Seattle, WA, United States.
William S BlanerDepartment of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, United States.
Case Western Reserve University · USColumbia University · USColumbia University Irving Medical Center · USUniversity of Washington · US
Funding
Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0MPOSTDOCTORAL TRAINING IN ARTERIOSCLEROSIS RESEARCHT32HL007343 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI HENRY N GINSBERG, Muredach P Reilly · 1985 to 2026
$12.7MThe Organoid and Cell Culture CoreP30DK132710 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Jianwen Que · 2022 to 2026
$7.2MPostprandial Vitamin AR01DK068437 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BLANER, WILLIAM S · 2004 to 2023
$7.0MRBP2 Biology and PathobiologyR01DK122071 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WILLIAM S BLANER, Marcin Bernard Golczak · 2019 to 2026
$4.6MAlcohol, Retinoids and Pancreas BiologyR21AA028110 · NIAAA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BLANER, WILLIAM S · 2019 to 2020
$425kNCATS NIH HHS UL1 TR001873NHLBI NIH HHS T32 HL007343NIAAA NIH HHS R21 AA028110NIDDK NIH HHS P30 DK132710NIDDK NIH HHS R01 DK068437NIDDK NIH HHS R01 DK122071
6 · The paper itselfAbstract
backgroundRetinol-binding protein 2 (RBP2) is an intracellular carrier for vitamin A in the absorptive enterocytes. Mice lacking RBP2 (Rbp2
objectivesGiven RBP2's role in intracellular retinoid trafficking, we aimed to evaluate whether dietary vitamin A affects incretin-secreting cell function and gene expression.
methodsMale Rbp2
resultsRbp2
conclusionsOur data support a role for RBP2 and dietary vitamin A in incretin secretion and gene expression in mice fed a HFD.
Indexed as
Diet, High-FatIncretinsAnimalsBlood GlucoseEnteroendocrine CellsGastric Inhibitory PolypeptideGlucagon-Like Peptide 1InsulinMaleMiceVitamin ABlood GlucoseGastric Inhibitory PolypeptideGlucagon-Like Peptide 1IncretinsInsulinVitamin Aenteroendocrine cellsglucagon-like peptide-1glucose-dependent insulinotropic polypeptideincretinsretinoidsretinol-binding protein 2
Identifiers
PMID37648113
PMCPMC10613727
OpenAlexW4386226722
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