Evidence map›Paper›PMID 37649788›Full record

ArticleTransplantation direct2023

Analysis of Individual Components of Frailty in Simultaneous Pancreas and Kidney, and Solitary Pancreas Transplant Recipients.

Sandesh Parajuli, Jon Odorico, Isabel Breyer, Emily Zona, Fahad Aziz, Heather Lorden, Jacqueline Garonzik-Wang, Dixon Kaufman, Didier Mandelbrot

Open access · goldAbstract read
In one paragraph

Article in Transplantation direct, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sandesh ParajuliDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Jon OdoricoUW Health Transplant Center.
Isabel BreyerDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Emily ZonaDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Fahad AzizDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Heather LordenUW Health Transplant Center.
Jacqueline Garonzik-WangUW Health Transplant Center.
Dixon KaufmanUW Health Transplant Center.
Didier MandelbrotDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
University of Wisconsin–Madison · USUniversity of Wisconsin Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Backgrounds: It is not known which of the 5 components of the Fried frailty score have the most predictive value for outcomes in simultaneous pancreas-kidney transplant (SPK) and solitary pancreas transplant (SPT) recipients. Methods: In this study, we sought to investigate the association between pretransplant overall frailty and individual frailty components, with posttransplant outcomes among SPK and SPT recipients. Outcomes of interest were length of stay, kidney delayed graft function (K-DGF), readmission within 30 d after discharge, cardiovascular events, acute rejection, pancreas death-censored graft failure (DCGF), kidney DCGF, and death. Results: Of the individual frailty components among SPK (n = 113), only slow walk time was associated with an increased risk of mortality (adjusted odds ratio [aOR]: 4.99; Conclusions: We found that not all components of frailty contribute equally to predicting outcomes. Objective measurements of slow walk time, unintentional weight loss, and low grip strength were found to be associated with less optimal outcomes in pancreas transplant recipients. Targeted interventions may improve posttransplant outcomes.

Identifiers

PMID37649788
PMCPMC10465099
OpenAlexW4386252962

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.