Evidence map›Paper›PMID 37650930›Full record

ArticleCalcified tissue international2023

Association of Immune Cell Subsets with Incident Hip Fracture: The Cardiovascular Health Study.

Rachel E Elam, Petra Bůžková, Joseph A C Delaney, Howard A Fink, Joshua I Barzilay, Laura D Carbone, Rick Saha, John A Robbins, Kenneth J Mukamal, Rodrigo J Valderrábano and 7 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Calcified tissue international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
  2. Osteo-Immunology and Hip Fractures.Calcified tissue international · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 2 countries.

Rachel E ElamDivision of Rheumatology, Department of Medicine, Augusta University, Augusta, GA, USA. relam@augusta.edu.ORCID 0000-0001-9927-6063
Petra BůžkováDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
Joseph A C DelaneyCardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.
Howard A FinkGeriatric Research Education and Clinical Center, Veterans Affairs Health Care System, Minneapolis, MN, USA.
Joshua I BarzilayDivision of Endocrinology, Kaiser Permanente of Georgia, Emory University School of Medicine, Atlanta, GA, USA.
Laura D CarboneDivision of Rheumatology, Department of Medicine, Augusta University, Augusta, GA, USA.
Rick SahaDepartment of Internal Medicine, New York University Langone, New York, NY, USA.
John A RobbinsDepartment of Medicine, University of California Davis, Davis, CA, USA.
Kenneth J MukamalDepartment of Medicine, Beth Israel Deaconess Medical Center, Brookline, MA, USA.
Rodrigo J ValderrábanoDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Bruce M PsatyCardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.
Russell P TracyDepartment of Pathology and Laboratory Medicine, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, USA.
Nels C OlsonDepartment of Pathology and Laboratory Medicine, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, USA.
Sally A HuberDepartment of Pathology and Laboratory Medicine, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, USA.
Margaret F DoyleDepartment of Pathology and Laboratory Medicine, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, USA.
Alan L LandayDepartment of Internal Medicine, Rush University Medical Center, Chicago, IL, USA.
Jane A CauleyDepartment of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
University of Vermont · USUniversity of Washington · USAugusta University · USBeth Israel Deaconess Medical Center · USBrigham and Women's Hospital · USGeriatric Research Education and Clinical Center · USKaiser Permanente · USNYU Langone Health · USRush University Medical Center · USUniversity of California, Davis · USUniversity of Pittsburgh · US

Funding

Exceptional Survival: Trajectories to Functional Aging (CHS All Stars)R01AG023629 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NEWMAN, ANNE B. · 2004 to 2016
$9.5M
CARDIOVASCULAR HEALTH STUDY (CHS) - TASK AREA C, STUDY CLOSEOUT75N92021D00006 · NHLBI · UNIVERSITY OF WASHINGTON · PI PSATY, BRUCE · 2021 to 2024
$8.4M
CHS research resources for the cardiovascular health of older adultsU01HL130114 · NHLBI · UNIVERSITY OF WASHINGTON · PI BURKE, GREGORY L, KRONMAL, RICHARD A · 2016 to 2019
$6.6M
CHS Events Follow-up StudyU01HL080295 · NHLBI · UNIVERSITY OF WASHINGTON · PI PSATY, BRUCE M · 2005 to 2008
$4.6M
Innate and adaptive immune-cell densities as risk factors for heart failureR01HL135625 · NHLBI · UNIVERSITY OF WASHINGTON · PI PSATY, BRUCE M, TRACY, RUSSELL P · 2018 to 2021
$2.8M
T-cell subsets as CVD risk factors in CHS and MESAR01HL120854 · NHLBI · UNIVERSITY OF WASHINGTON · PI PSATY, BRUCE M, TRACY, RUSSELL P · 2014 to 2017
$2.6M
Intermediate neuronal progenitors in neocortical developmentR01NS085081 · NINDS · SEATTLE CHILDREN'S HOSPITAL · PI HEVNER, ROBERT F · 2013 to 2017
$2.1M
Role of EIIIA fibronectin in pulmonary fibrosisR01HL085083 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WHITE, ERIC S · 2007 to 2011
$1.9M
CHS-Transition PhaseN01HC55222 · NHLBI · PI , · 2007 to 2007
$575k
CORONARY HEART DISEASE &STROKE IN THE ELDERLYN01HC085080 · HC · WAKE FOREST UNIVERSITY · PI BURKE, GREGORY L · 1988 to 2000
–
CHS-Transition Phase -268055222-268055222N01HC055222 · HC · UNIVERSITY OF WASHINGTON · PI KRONMAL, RICHARD A · 2005 to 2006
–
CORONARY HEART DISEASE &STROKE IN PEOPLE AGED 65-84N01HC085081 · HC · JOHNS HOPKINS UNIVERSITY · PI FRIED, LINDA P · 1988 to 2000
–
NHLBI NIH HHS 75N92021D00006NHLBI NIH HHS contracts HHSN268201200036CNHLBI NIH HHS grants U01HL080295NHLBI NIH HHS HHSN268200800007CNHLBI NIH HHS HHSN268201200036CNHLBI NIH HHS HHSN268201800001CNHLBI NIH HHS N01 HC055222NHLBI NIH HHS N01 HC085079NHLBI NIH HHS N01 HC085080NHLBI NIH HHS N01 HC085081NHLBI NIH HHS N01 HC085082NHLBI NIH HHS N01 HC085083NHLBI NIH HHS N01 HC085086NHLBI NIH HHS R01 HL120854NHLBI NIH HHS R01HL120854NHLBI NIH HHS R01 HL135625NHLBI NIH HHS R01HL135625NHLBI NIH HHS U01 HL080295NHLBI NIH HHS U01 HL130114NHLBI NIH HHS U01HL130114NIA NIH HHS R01 AG023629NIA NIH HHS R01AG023629NINDS NIH HHS 75N92021D00006NINDS NIH HHS contracts HHSN268201200036CNINDS NIH HHS grants U01HL080295NINDS NIH HHS HHSN268200800007CNINDS NIH HHS HHSN268201800001CNINDS NIH HHS N01HC55222NINDS NIH HHS N01HC85079NINDS NIH HHS N01HC85080NINDS NIH HHS N01HC85081NINDS NIH HHS N01HC85082NINDS NIH HHS N01HC85083NINDS NIH HHS N01HC85086NINDS NIH HHS U01HL130114
6 · The paper itself

Abstract

In this study, we aimed to evaluate the association of innate and adaptive immune cell subsets in peripheral blood mononuclear cells (PBMCs) with hip fracture. To conduct this study, we used data from the Cardiovascular Health Study (CHS), a U.S. multicenter observational cohort of community-dwelling men and women aged ≥ 65 years. Twenty-five immune cell phenotypes were measured by flow cytometry from cryopreserved PBMCs of CHS participants collected in 1998-1999. The natural killer (NK), γδ T, T helper 17 (Th17), and differentiated/senescent CD4

Indexed as

Hip FracturesLeukocytes, MononuclearAgedFemaleHumansIncidenceMaleProspective StudiesRisk FactorsBiomarkersFractureImmunityInflammationOsteoporosisRisk factors

Identifiers

PMID37650930
PMCPMC11229516
OpenAlexW4386306298

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.