Evidence map›Paper›PMID 37652499›Full record

Trial reportIn vivo (Athens, Greece)

Highlighting the Advantages and Benefits of Non-NSAID Treatment After Total Knee Arthroplasty: A Cross-sectional Study.

Gelu Florin Murvai, Calin Tudor Hozan, Calin Magheru, Gheorghe Szilagyi, Madalin Bulzan, Viorela Romina Murvai, Simona Cavalu, Timea Claudia Ghitea

Open access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The Effect ofIn vivo (Athens, Greece)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Gelu Florin MurvaiMedicine Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
Calin Tudor HozanOrthopedics and Traumatology Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
Calin MagheruMedicine Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
Gheorghe SzilagyiMedicine Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
Madalin BulzanMedicine Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
Viorela Romina MurvaiMedicine Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
Simona CavaluOrthopedics and Traumatology Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
Timea Claudia GhiteaDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania timea.ghitea@csud.uoradea.ro.
University of Oradea · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimOsteoarthritis is one of the most common degenerative conditions that causes pain, stiffness, and decreased functionality. The management of knee osteoarthritis necessitates collaboration among specialists from different disciplines, considering the primary clinical manifestations and functional level of the disease. The aim of this study was to highlight the disparities in postoperative outcomes between knee arthroplasty procedures with and without non-steroidal anti-inflammatory drugs (NSAIDs). The study specifically focuses on the immediate advantages and outcomes observed at the 6-month milestone. PATIENTS AND

methodsThis study followed 713 patients who were randomly divided into two groups: a group that did not receive non-steroidal anti-inflammatory drugs (N-NSAIDs) consisting of 394 patients, and a group that received non-steroidal anti-inflammatory drugs (NSAIDs) comprising 319 patients. The study spanned a duration of 5 years (2018-2022), with patients being followed and evaluated for up to 6 months after the surgery.

resultsIt was observed that, from a therapeutic standpoint, the use of injectable treatments decreased. Significantly better differences were recorded in the N-NSAIDs group regarding return to pre-osteoarthritis activities at 6 months and reduced or absent night pain at 3 months (p<0.05).

conclusionStatistically significant improvements were observed in the N-NSAIDs group concerning the ability to resume pre-osteoarthritis activities within 6 months, as well as a reduction or absence of nighttime pain within 3 months.

Indexed as

Arthroplasty, Replacement, KneeOsteoarthritis, KneeAnti-Inflammatory Agents, Non-SteroidalCross-Sectional StudiesHumansPainAnti-Inflammatory Agents, Non-SteroidalbenefitsgonarthrosisNSAIDsorthopedic surgeryOsteoarthritis of the knee

Identifiers

PMID37652499
PMCPMC10500518
OpenAlexW4386347839

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.