Evidence map›Paper›PMID 37655336›Full record

ArticleActa pharmaceutica Sinica. B2023

Hepatic DDAH1 mitigates hepatic steatosis and insulin resistance in obese mice: Involvement of reduced S100A11 expression.

Xiyue Shen, Kai Luo, Juntao Yuan, Junling Gao, Bingqing Cui, Zhuoran Yu, Zhongbing Lu

Open access · diamondAbstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiyue ShenCollege of Life Science, University of Chinese Academy of Sciences, Beijing 100049, China.
Kai LuoCollege of Life Science, University of Chinese Academy of Sciences, Beijing 100049, China.
Juntao YuanCollege of Life Science, University of Chinese Academy of Sciences, Beijing 100049, China.
Junling GaoCollege of Life Science, University of Chinese Academy of Sciences, Beijing 100049, China.
Bingqing CuiCollege of Life Science, University of Chinese Academy of Sciences, Beijing 100049, China.
Zhuoran YuCollege of Life Science, University of Chinese Academy of Sciences, Beijing 100049, China.
Zhongbing LuCollege of Life Science, University of Chinese Academy of Sciences, Beijing 100049, China.
University of Chinese Academy of Sciences · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dimethylarginine dimethylaminohydrolase 1 (DDAH1) is an important regulator of plasma asymmetric dimethylarginine (ADMA) levels, which are associated with insulin resistance in patients with nonalcoholic fatty liver disease (NAFLD). To elucidate the role of hepatic DDAH1 in the pathogenesis of NAFLD, we used hepatocyte-specific

Indexed as

ADMADDAH1Hepatic steatosisHigh fat dietInflammationInsulin resistanceOxidative stressS100A11

Identifiers

PMID37655336
PMCPMC10465955
OpenAlexW4378085452

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.