Evidence map›Paper›PMID 37656151›Full record

SynthesisAnaesthesia2023

Peri-operative tobacco cessation interventions: a systematic review and meta-analysis.

S Harrogate, J Barnes, K Thomas, A Isted, G Kunst, S Gupta, S Rudd, T Banerjee, R Hinchliffe, R Mouton

Open access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Anaesthesia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. The impact of anesthesia instruments and drugs on the occurrence of vocal cord injury, systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Unraveling the Enigmatic Behavior ofInternational journal of microbiology · 2026
    Article
  7. Observational
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

S HarrogateElizabeth Blackwell Institute, University of Bristol, Bristol, UK.ORCID 0000-0003-0584-0079
J BarnesDepartment of Anaesthesia, North Bristol NHS Trust, Bristol, UK.
K ThomasDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
A IstedDepartment of Anaesthesia, King's College Hospital NHS Foundation Trust, London, UK.
G KunstSchool of Cardiovascular and Metabolic Medicine and Sciences, King's College London, London, UK.
S GuptaDepartment of Anaesthesia, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
S RuddNorth Bristol NHS Trust, Bristol, UK.
T BanerjeeUniversity of Leicester, Leicester, UK.
R HinchliffeDepartment of Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
R MoutonDepartment of Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
North Bristol NHS Trust · GBKing's College Hospital NHS Foundation Trust · GBKing's College London · GBUniversity Hospitals Bristol NHS Foundation Trust · GBUniversity of Bristol · GBUniversity of Leicester · GB

Funding

Wellcome TrustWellcome Trust 204813/Z/16/Z
6 · The paper itself

Abstract

Tobacco smoking is associated with a substantially increased risk of postoperative complications. The peri-operative period offers a unique opportunity to support patients to stop tobacco smoking, avoid complications and improve long-term health. This systematic review provides an up-to-date summary of the evidence for tobacco cessation interventions in surgical patients. We conducted a systematic search of randomised controlled trials of tobacco cessation interventions in the peri-operative period. Quantitative synthesis of the abstinence outcomes data was by random-effects meta-analysis. The primary outcome of the meta-analysis was abstinence at the time of surgery, and the secondary outcome was abstinence at 12 months. Thirty-eight studies are included in the review (7310 randomised participants) and 26 studies are included in the meta-analysis (5969 randomised participants). Studies were pooled for subgroup analysis in two ways: by the timing of intervention delivery within the peri-operative period and by the intensity of the intervention protocol. We judged the quality of evidence as moderate, reflecting the degree of heterogeneity and the high risk of bias. Overall, peri-operative tobacco cessation interventions increased successful abstinence both at the time of surgery, risk ratio (95%CI) 1.48 (1.20-1.83), number needed to treat 7; and 12 months after surgery, risk ratio (95%CI) 1.62 (1.29-2.03), number needed to treat 9. More work is needed to inform the design and optimal delivery of interventions that are acceptable to patients and that can be incorporated into contemporary elective and urgent surgical pathways. Future trials should use standardised outcome measures.

Indexed as

Tobacco Use CessationHumansPerioperative CarePostoperative ComplicationsRandomized Controlled Trials as Topicabstinenceaddictionmeta-analysisperi-operative tobacco cessation interventionssystematic review

Identifiers

PMID37656151
PMCPMC10952322
OpenAlexW4386347898

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.