Evidence map›Paper›PMID 37656229›Full record

ArticlePflugers Archiv : European journal of physiology2023

Normobaric hypoxia shows enhanced FOXO1 signaling in obese mouse gastrocnemius muscle linked to metabolism and muscle structure and neuromuscular innervation.

Jingyi Song, Loes P M Duivenvoorde, Sander Grefte, Ondrej Kuda, Felipe Martínez-Ramírez, Inge van der Stelt, Dimitra Mastorakou, Evert M van Schothorst, Jaap Keijer

Open access · hybridAbstract read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jingyi Song *Human and Animal Physiology, Wageningen University, Wageningen, The Netherlands.
Loes P M Duivenvoorde *Human and Animal Physiology, Wageningen University, Wageningen, The Netherlands.
Sander GrefteHuman and Animal Physiology, Wageningen University, Wageningen, The Netherlands.
Ondrej KudaLaboratory of Metabolism of Bioactive Lipids, Institute of Physiology, Czech Academy of Sciences, 14220, Prague 4, Czech Republic.
Felipe Martínez-RamírezLaboratory of Metabolism of Bioactive Lipids, Institute of Physiology, Czech Academy of Sciences, 14220, Prague 4, Czech Republic.
Inge van der SteltHuman and Animal Physiology, Wageningen University, Wageningen, The Netherlands.
Dimitra MastorakouLaboratory of Metabolism of Bioactive Lipids, Institute of Physiology, Czech Academy of Sciences, 14220, Prague 4, Czech Republic.
Evert M van SchothorstHuman and Animal Physiology, Wageningen University, Wageningen, The Netherlands.
Jaap KeijerHuman and Animal Physiology, Wageningen University, Wageningen, The Netherlands. jaap.keijer@wur.nl.
Wageningen University & Research · NLCzech Academy of Sciences · CZCzech Academy of Sciences, Institute of Physiology · CZ

Funding

China Scholarship Council 201908110278Czech Academy of Sciences Lumina Quaeruntur LQ200111901European Union's Seventh Framework Programme FP7 2007-2013 244995 (BIOCLAIMS Project)
6 · The paper itself

Abstract

Skeletal muscle relies on mitochondria for sustainable ATP production, which may be impacted by reduced oxygen availability (hypoxia). Compared with long-term hypoxia, the mechanistic in vivo response to acute hypoxia remains elusive. Therefore, we aimed to provide an integrated description of the Musculus gastrocnemius response to acute hypoxia. Fasted male C57BL/6JOlaHsd mice, fed a 40en% fat diet for six weeks, were exposed to 12% O

Indexed as

Forkhead Box Protein O1HypoxiaMuscle, SkeletalObesityAnimalsEnergy MetabolismMaleMiceMice, Inbred C57BLMice, ObeseSignal TransductionForkhead Box Protein O1Foxo1 protein, mouseFOXOHypoxiaMetabolismMitochondriaNeuromuscular junctionSkeletal muscle

Identifiers

PMID37656229
PMCPMC10567817
OpenAlexW4386347617

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.