Evidence map›Paper›PMID 37659249›Full record

ReviewSleep medicine reviews2023

Dietary polyphenols and sleep modulation: Current evidence and perspectives.

Jara Pérez-Jiménez, Kaitha Agnant, Rosa M Lamuela-Raventós, Marie-Pierre St-Onge

Open access · greenAbstract readReview
In one paragraph

Review in Sleep medicine reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Jara Pérez-JiménezDept. Metabolism and Nutrition, Institute of Food Science, Technology and Nutrition (ICTAN-CSIC), Madrid, Spain; CIBER of Diabetes and Associated Metabolic Disease (CIBERDEM), ISCIII, Madrid, Spain; Division of General Medicine and Center of Excellence for Sleep & Circadian Research, Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA.
Kaitha AgnantDivision of General Medicine and Center of Excellence for Sleep & Circadian Research, Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA.
Rosa M Lamuela-RaventósDept. Nutrition, Food Sciences and Gastronomy, XIA, INSA-UB, School of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain; CIBER Physiopathology of Obesity and Nutrition (CIBER-OBN), ISCIII, Madrid, Spain.
Marie-Pierre St-OngeDivision of General Medicine and Center of Excellence for Sleep & Circadian Research, Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA. Electronic address: ms2554@cumc.columbia.edu.
Columbia University · USColumbia University Irving Medical Center · USInstituto de Salud Carlos III · ESMadrid Institute for Advanced Studies · ES

Funding

Mediterranean diet, Metabolites, and Cardiovascular DiseaseR01HL118264 · NHLBI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI HU, FRANK B, LAMUELA-RAVENTÓS, ROSA · 2013 to 2025
$6.8M
Mechanisms addressing the causal relationships of sleep, circadian rhythms, and cardiometabolic healthR35HL155670 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARIE-PIERRE ST-ONGE · 2021 to 2026
$5.4M
Impact of circadian misalignment on energy balance regulationR01HL142648 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ST-ONGE, MARIE-PIERRE · 2018 to 2022
$3.8M
NHLBI NIH HHS R01 HL118264NHLBI NIH HHS R01 HL142648NHLBI NIH HHS R35 HL155670
6 · The paper itself

Abstract

Polyphenols are plant compounds with several biological activities. This review aims to summarize current knowledge on the potential role of polyphenols in modulating sleep. A total of 28 preclinical studies, 12 intervention studies and four observational studies exploring the role of polyphenol intake on sleep were identified. From animal studies, 26 out of the 28 studies found beneficial effects of polyphenols on sleep architecture. Three out of four human observational studies found a beneficial association between polyphenol intake and sleep parameters. And, among clinical intervention studies, eight from a total of 12 studies found some beneficial effect of polyphenol intake on various sleep parameters, although some discrepancies between studies were found. Overall, emerging evidence suggests a benefit of polyphenol intake on sleep. Several mechanisms of action have been suggested, ranging from effects on neurotransmitters to an action through the gut-brain axis. However, more research in this field is needed, emphasizing the use of nutritional doses in mechanistic studies and interventions targeting participants with sleep problems. This would allow to elucidate whether an additional biological effect of polyphenols is modulation of sleep, a behavior associated with adverse health outcomes.

Indexed as

DietPolyphenolsSleepAnimalsHumansPolyphenolsClinical trialsFood bioactive compoundsInsomniaPolyphenolsSleep

Identifiers

PMID37659249
PMCPMC10872761
OpenAlexW4386226982

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.