Evidence map›Paper›PMID 37662903›Full record

ReviewFrontiers in immunology2023

Cell-targeted vaccines: implications for adaptive immunity.

Trevor Ung, Nakisha S Rutledge, Adam M Weiss, Aaron P Esser-Kahn, Peter Deak

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Trevor UngPritzker School of Molecular Engineering, University of Chicago, Chicago, IL, United States.
Nakisha S RutledgePritzker School of Molecular Engineering, University of Chicago, Chicago, IL, United States.
Adam M WeissPritzker School of Molecular Engineering, University of Chicago, Chicago, IL, United States.
Aaron P Esser-KahnPritzker School of Molecular Engineering, University of Chicago, Chicago, IL, United States.
Peter DeakChemical and Biological Engineering Department, Drexel University, Philadelphia, PA, United States.
University of Chicago · USDrexel University · US

Funding

Immunoengineering Postdoctoral Training Program - Resubmission - 1T32AI153020 · NIAID · UNIVERSITY OF CHICAGO · PI ALEGRE, MARIA-LUISA, SWARTZ, MELODY ANN · 2021 to 2025
$2.1M
NIAID NIH HHS T32 AI153020
6 · The paper itself

Abstract

Recent advancements in immunology and chemistry have facilitated advancements in targeted vaccine technology. Targeting specific cell types, tissue locations, or receptors can allow for modulation of the adaptive immune response to vaccines. This review provides an overview of cellular targets of vaccines, suggests methods of targeting and downstream effects on immune responses, and summarizes general trends in the literature. Understanding the relationships between vaccine targets and subsequent adaptive immune responses is critical for effective vaccine design. This knowledge could facilitate design of more effective, disease-specialized vaccines.

Indexed as

VaccinesAnimalsDrug DesignHumansImmune SystemImmunityVaccinesadaptive immunitycell targetinginnate immunitytargeted vaccinesvaccine

Identifiers

PMID37662903
PMCPMC10468591
OpenAlexW4385954815

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.