Evidence map›Paper›PMID 37664375›Full record

ReviewCureus2023

Unlocking the Potential of Immunotherapy in Cardiovascular Disease: A Comprehensive Review of Applications and Future Directions.

Fnu Jyotsna, Jibran Ikram, Fnu Nageeta, Fnu Komal, Fnu Anjlee, Harshkumar Patel, Taleb Nassri, Meena Kumari, Rajesh Kumar, Syeda Urooba Shah and 4 more

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 4 countries.

Fnu JyotsnaMedicine, Dr. B.R. Ambedkar Medical College & Hospital, Mohali, IND.
Jibran IkramOrthopaedics and Trauma, Rehman Medical Institute, Peshawar, PAK.
Fnu NageetaMedicine, Ghulam Muhammad Mahar Medical College, Sukkur, PAK.
Fnu KomalMedicine, Chandka Medical College, Larkana, PAK.
Fnu AnjleeMedicine, Ghulam Muhammad Mahar Medical College, Sukkur, PAK.
Harshkumar PatelInternal Medicine, PDU (Pandit Dindayal Upadhyay) Medical College, Rajkot, IND.
Taleb NassriMedicine, Heart and Vascular Institute, Dearborn, USA.
Meena KumariInternal Medicine, Dow University of Health Sciences, Karachi, PAK.
Rajesh KumarBusiness Intelligence and Data Analytics, Westcliff University, Irvine, USA.
Syeda Urooba ShahMedicine, Jinnah Sindh Medical University, Karachi, PAK.
Maham KashifMedicine, Khawaja Muhammad Safdar Medical College, Wazirabad, PAK.
Giustino VarrassiPain Medicine, Paolo Procacci Foundation, Rome, ITA.
Satesh KumarMedicine and Surgery, Shaheed Mohtarma Benazir Bhutto Medical College, Karachi, PAK.
Tirath PatelMedicine, American University of Antigua, St. John, ATG.
Sree Gokulam Medical College and Research Foundation · INAmerican University of Antigua · AGChandka Medical College · PKDow University of Health Sciences · PKFondazione Roma · ITJinnah Sindh Medical University · PKShaheed Mohtarma Benazir Bhutto Medical University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy has emerged as a pioneering therapeutic approach that harnesses the immune system's abilities to combat diseases, particularly in the field of oncology where it has led to significant advancements. However, despite its significant impact in the field of oncology, the potential of immunotherapy in the context of cardiovascular disease (CVD) has not been thoroughly investigated. The purpose of this narrative review is to address the existing knowledge and potential uses of immunotherapy in the field of cardiovascular disease (CVD), with the intention of filling the existing gap in understanding. Furthermore, the review thoroughly examines the future prospects of this swiftly advancing field, providing insights into the aspects that necessitate further investigation and addressing the forthcoming challenges. The review is organized into four distinct sections to enhance comprehension. The first section introduces immunotherapy, presenting the fundamental concepts and principles. The second section explores the immunomodulatory mechanisms in cardiovascular disease (CVD), with a specific focus on the intricate interplay between the immune system and the development of cardiovascular pathogenesis. The utilization of immunotherapy in specific cardiovascular conditions will be examined, investigating the application of immunotherapy in the context of different cardiovascular diseases. The future prospects and challenges in immunotherapy for cardiovascular diseases will be discussed, highlighting the potential areas for future research and addressing the barriers that must be overcome to effectively implement immunotherapeutic interventions in the management of cardiovascular diseases.

Indexed as

applicationscardiac risk factors and preventioncardiovascularimmuneimmunotherapytherapeutic

Identifiers

PMID37664375
PMCPMC10469982
OpenAlexW4385456379

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.