Evidence map›Paper›PMID 37664862›Full record

ReviewFrontiers in endocrinology2023

Zebrafish as an emerging model to study estrogen receptors in neural development.

Marie-José Boueid, Océane El-Hage, Michael Schumacher, Cindy Degerny, Marcel Tawk

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marie-José BoueidU1195, Inserm, University Paris-Saclay, Le Kremlin Bicêtre, France.
Océane El-HageU1195, Inserm, University Paris-Saclay, Le Kremlin Bicêtre, France.
Michael SchumacherU1195, Inserm, University Paris-Saclay, Le Kremlin Bicêtre, France.
Cindy DegernyU1195, Inserm, University Paris-Saclay, Le Kremlin Bicêtre, France.
Marcel TawkU1195, Inserm, University Paris-Saclay, Le Kremlin Bicêtre, France.
Université Paris-Saclay · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estrogens induce several regulatory signals in the nervous system that are mainly mediated through estrogen receptors (ERs). ERs are largely expressed in the nervous system, yet the importance of ERs to neural development has only been elucidated over the last decades. Accumulating evidence shows a fundamental role for estrogens in the development of the central and peripheral nervous systems, hence, the contribution of ERs to neural function is now a growing area of research. The conservation of the structure of the ERs and their response to estrogens make the zebrafish an interesting model to dissect the role of estrogens in the nervous system. In this review, we highlight major findings of ER signaling in embryonic zebrafish neural development and compare the similarities and differences to research in rodents. We also discuss how the recent generation of zebrafish ER mutants, coupled with the availability of several transgenic reporter lines, its amenability to pharmacological studies and

Indexed as

Receptors, EstrogenZebrafishAnimalsAnimals, Genetically ModifiedEstrogensNeurogenesisEstrogensReceptors, Estrogenestrogen (17β-estradiol)estrogen receptor - ESRgliaGPERneurogenesisnotcholigodendrocyte (OL)zebrafish

Identifiers

PMID37664862
PMCPMC10469878
OpenAlexW4385984406

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.