Evidence map›Paper›PMID 37673035›Full record

ArticleCell metabolism2023

The neurocircuitry of fasting-induced glucocorticoid release.

Nikolai P Jaschke, Andrew Wang

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Nikolai P JaschkeDivision of Endocrinology, Department of Medicine III, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA. Electronic address: nikolai.jaschke@uniklinikum-dresden.de.
Andrew WangDepartment of Immunobiology, Yale School of Medicine, New Haven, CT, USA.

Funding

Dissecting How Xenobiotics Act as Adjuvants for Oral Allergic SensitizationR01AI162645 · NIAID · YALE UNIVERSITY · PI Andrew Wang · 2021 to 2026
$3.6M
The Role of the Adrb3/IL6 Axis in the Impact of Psychosocial Stress on Lupus PathogenesisR01AR080104 · NIAMS · YALE UNIVERSITY · PI Andrew Wang · 2022 to 2026
$2.2M
NIAID NIH HHS R01 AI162645NIAMS NIH HHS R01 AR080104
6 · The paper itself

Abstract

Activation of the hypothalamus-pituitary-adrenal gland (HPA) axis confers adaptations to homeostatic perturbations including food scarcity. A comprehensive new study by Douglass et al. disentangled how agouti-related peptide (AgRP)-expressing neurons of the arcuate nucleus (ARC) trigger rapid HPA-axis activation in response to fasting, which is mediated by repression of a tonic, inhibitory neuro circuit.

Indexed as

AcclimatizationGlucocorticoidsArcuate Nucleus of HypothalamusFastingHomeostasisGlucocorticoids

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.