Evidence map›Paper›PMID 37674033›Full record

SynthesisInternational journal of obesity (2005)2023

Effects of probiotics in patients with morbid obesity undergoing bariatric surgery: a systematic review and meta-analysis.

Yuting Wang, Youwei Zheng, Lirun Kuang, Keyu Yang, Jiaji Xie, Xinde Liu, Shan Shen, Xinchao Li, Shiran Wu, Yuyi Yang and 3 more

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of obesity (2005), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Observational
  8. Review
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  11. Review
  12. Article
  13. The impact of probiotics on glycemic control during the first 3 months after sleeve gastrectomy: a prospective placebo‑controlled study.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025
    Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Yuting WangDepartment of General Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110032, China.
Youwei ZhengDepartment of General Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110032, China.
Lirun KuangDepartment of General Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110032, China.
Keyu YangDepartment of General Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110032, China.
Jiaji XieDepartment of General Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110032, China.
Xinde LiuDepartment of General Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110032, China.
Shan ShenDepartment of General Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110032, China.
Xinchao LiDepartment of General Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110032, China.
Shiran WuDepartment of General Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110032, China.
Yuyi YangDepartment of General Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110032, China.
Jiafei ShiDepartment of General Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110032, China.
Jialiang WuDepartment of General Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110032, China.
Yong WangDepartment of General Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110032, China. wangyong@cmu.edu.cn.
China Medical University · CNFourth Affiliated Hospital of China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProbiotics are commonly used after bariatric surgery. However, uncertainty remains regarding their effects. The purpose of this systematic review was to assess the effect of probiotics in patients with morbid obesity undergoing bariatric surgery.

methodsPubMed, Cochrane Library, Embase, Science Direct, and Web of Science were searched from inception to April 4, 2023. No language restrictions were applied. Relevant randomized controlled trials and controlled clinical trials were included. We used the aggregated data extracted from the trials and assessed the heterogeneity. When severe heterogeneity was detected, a random effect model was used. All stages of the review were done by independent authors.

resultsWe screened 2024 references and included 11 randomized controlled trials and controlled clinical trials. Compared with the protocol groups, probiotics showed significant effects on regulating aspartate amino transferase level (MD = -4.32 U/L; 95% CI [-7.10, -1.53], p = 0.002), triglycerides (MD = -20.16 mg/dL; 95% CI [-34.51, -5.82], p = 0.006), weight (MD = -1.99 kg; 95% CI [-3.97, -0.01], p = 0.05), vitamin B

conclusionsOur meta-analysis suggested that probiotics may delay the progression of liver function injury, improve lipid metabolism, reduce weight, and reduce food intake, although the effects on other indicators were insignificant. Probiotics may be helpful for patients undergoing bariatric surgery. The review was registered on PROSPERO (International prospective register of systematic reviews): CRD42023407970. No primary source of funding.

Indexed as

Bariatric SurgeryObesity, MorbidProbioticsDietary FiberHumansLiverDietary Fiber

Identifiers

PMID37674033
PMCPMC10600003
OpenAlexW4386483851

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.