Evidence map›Paper›PMID 37674073›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2023

Visual field after anti-vascular endothelial growth factor therapy and laser treatment for retinopathy of prematurity.

Shumpei Obata, Riko Matsumoto, Maki Iwasa, Masashi Kakinoki, Osamu Sawada, Tomoko Sawada, Yoshitsugu Saishin, Masahito Ohji

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07427719 (Children Treated for Retinopathy of Prematurity - Study of Visual Function and Retinal Structure), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07427719 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Children Treated for Retinopathy of Prematurity - Study of Visual Function and Retinal Structure

TypeobservationalSponsorOslo University HospitalRan2026 to 2029Enrolled140ConditionsRetinopathy of Prematurity (ROP), Prematurity Complications, Cerebral Visual Impairment, Visual Field Defect
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Efficacy, durability, and safety of faricimab up to every 16 weeks in patients with neovascular age-related macular degeneration: 2-year results from the Japan subgroup of the phase III TENAYA trial.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Trial
  2. Article
  3. Article
  4. Article
  5. Short-term outcomes of treatment switch to faricimab in patients with aflibercept-resistant neovascular age-related macular degeneration.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Observational
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shumpei ObataDepartment of Ophthalmology, Shiga University of Medical Science, Otsu, Japan. obata326@belle.shiga-med.ac.jp.ORCID http://orcid.org/0000-0001-6120-2392
Riko MatsumotoDepartment of Ophthalmology, Shiga University of Medical Science, Otsu, Japan.
Maki IwasaDepartment of Ophthalmology, Shiga University of Medical Science, Otsu, Japan.
Masashi KakinokiDepartment of Ophthalmology, Shiga University of Medical Science, Otsu, Japan.
Osamu SawadaDepartment of Ophthalmology, Shiga University of Medical Science, Otsu, Japan.
Tomoko SawadaDepartment of Ophthalmology, Shiga University of Medical Science, Otsu, Japan.
Yoshitsugu SaishinDepartment of Ophthalmology, Shiga University of Medical Science, Otsu, Japan.
Masahito OhjiDepartment of Ophthalmology, Shiga University of Medical Science, Otsu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the visual field after anti-vascular endothelial growth factor (VEGF) therapy and laser treatment for retinopathy of prematurity.

methodRetrospective cohort study. Infants with retinopathy of prematurity treated by anti-VEGF therapy or laser treatment were included in the study. Degrees of visual field in eight directions examined by Goldmann perimeter (intensity, 1000 apostilb; size, V4e = 64 mm

resultsNine eyes with anti-VEGF therapy and 12 eyes with laser treatment were enrolled in the analysis. The total, upper, nasal upper, nasal, nasal lower, temporal lower, and temporal upper visual fields were significantly wider in the eyes with anti-VEGF therapy than in those with laser treatment (496 vs 416, P = .002; 53 vs 45, P = .008; 56 vs 43, P = .003; 58 vs 39, P < .001; 55 vs 44, P = .01; 72 vs 65, P = .01; and 62 vs 56, P = .03, respectively). The logarithm of the minimum angle of resolution VA tended to be better in the eyes with anti-VEGF therapy than in those with laser treatment (0.01 vs 0.15, P = .06). Eyes with anti-VEGF therapy had significantly lower myopia than those with laser treatment (spherical equivalent refraction: -0.72 vs -5.7, P = .001).

conclusionAnti-VEGF therapy may provide a wider visual field, better VA, and less myopia compared with laser treatment.

Indexed as

BevacizumabLaser CoagulationRanibizumabRetinopathy of PrematurityVisual AcuityVisual FieldsAngiogenesis InhibitorsFemaleFollow-Up StudiesGestational AgeHumansInfant, NewbornIntravitreal InjectionsMaleReceptors, Vascular Endothelial Growth FactorRefraction, OcularAngiogenesis InhibitorsBevacizumabRanibizumabReceptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor ALaserRetinopathy of prematurityTreatmentVascular endothelial growth factorVisual field

Identifiers

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.