ArticleGut microbes2023
Obesity is the main driver of altered gut microbiome functions in the metabolically unhealthy.
Article in Gut microbes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- Gut microbiome and metabolic health: mechanisms and precision interventions.Gut microbes · 2026Review
- Network topology of the gut microbiome associates with metabolic health in obesity.Nature communications · 2026Article
- A Novel Strain Bifidobacterium longum subsp. longum HN001 Ameliorates High-Fat Diet-Induced Obesity in Mice Through Microbiome-Associated Short-Chain Fatty Acids.Probiotics and antimicrobial proteins · 2026Article
- A novel obesity index reveals obesity-associated microbiota changes after weight loss intervention in a Spanish population.Nutrition journal · 2026Article
- Common features in the gut microbiota of underweight and overweight individuals and patients with Parkinson's disease - a mini-review.Pharmacological reports : PR · 2026Review
- The Impact of Bariatric Surgery on the Development and Progression of Dermatologic Diseases: A Narrative Review.Dermatology and therapy · 2026Review
- Ultra-processed foods and accelerated aging in adults: an emerging public health challenge for nutrition and functional health.Frontiers in nutrition · 2026Review
- Structure-sensitive transformer and multi-view graph contrastive learning enhanced prediction of drug-related microbes.BMC bioinformatics · 2025Article
- Association of the Dietary Index for Gut Microbiota and Cardiovascular-Kidney-Metabolic Syndrome: The Mediation Effect of Phenotypic and Biological Age Acceleration, BMI, and BRI.Food science & nutrition · 2025Article
- Impact of aFoods (Basel, Switzerland) · 2025Article
- Harnessing the Power of Fermented Tea to Improve Gut Microbiota and Combat Obesity Epidemic.Biology · 2024Review
- Gut microbiome diversity withinmSystems · 2024Article
- Prediction of microbe-drug associations based on a modified graph attention variational autoencoder and random forest.Frontiers in microbiology · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity (OB) and cardiometabolic disease are major public health issues linked to changes in the gut microbiome. OB and poor cardiometabolic health status (CHS) are often comorbid, which hinders efforts to identify components of the microbiome uniquely linked to either one. Here, we used a deeply phenotyped cohort of 408 adults from Colombia, including subjects with OB, unhealthy CHS, or both, to validate previously reported features of gut microbiome function and diversity independently correlated with OB or CHS using fecal metagenomes. OB was defined by body mass index, waist circumference, and body fat; CHS as healthy or unhealthy according to blood biochemistry and anthropometric data. We found that OB, more so than metabolic status, drove associations with gut microbiome structure and functions. The microbiome of obese individuals with and without co-existing unhealthy CHS was characterized by reduced metagenomic diversity, reduced fermentative potential and elevated capacity to respond to oxidative stress and produce bacterial antigens. Disease-linked features were correlated with increased host blood pressure and inflammatory markers, and were mainly contributed by members of the family
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.