Evidence map›Paper›PMID 37681145›Full record

ArticleHeliyon2023

TRAF3 deficiency in MDCK cells improved sensitivity to the influenza A virus.

Yang Le, Jiayou Zhang, Zheng Gong, Zhegang Zhang, Xuanxuan Nian, Xuedan Li, Daiguan Yu, Ning Ma, Rong Zhou, Guomei Zhang and 5 more

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Yang LeNational Engineering Technology Research Center for Combined Vaccines, 430207, Wuhan, China.
Jiayou ZhangNational Engineering Technology Research Center for Combined Vaccines, 430207, Wuhan, China.
Zheng GongNational Engineering Technology Research Center for Combined Vaccines, 430207, Wuhan, China.
Zhegang ZhangNational Engineering Technology Research Center for Combined Vaccines, 430207, Wuhan, China.
Xuanxuan NianNational Engineering Technology Research Center for Combined Vaccines, 430207, Wuhan, China.
Xuedan LiNational Engineering Technology Research Center for Combined Vaccines, 430207, Wuhan, China.
Daiguan YuNational Engineering Technology Research Center for Combined Vaccines, 430207, Wuhan, China.
Ning MaNational Engineering Technology Research Center for Combined Vaccines, 430207, Wuhan, China.
Rong ZhouNational Engineering Technology Research Center for Combined Vaccines, 430207, Wuhan, China.
Guomei ZhangNational Engineering Technology Research Center for Combined Vaccines, 430207, Wuhan, China.
Bo LiuNational Engineering Technology Research Center for Combined Vaccines, 430207, Wuhan, China.
Lu YangNational Engineering Technology Research Center for Combined Vaccines, 430207, Wuhan, China.
Baiqi FuWuhan Institute of Biotechnology, Wuhan, 430075, China.
Xiuqin XuWuhan Institute of Biotechnology, Wuhan, 430075, China.
Xiaoming YangNational Engineering Technology Research Center for Combined Vaccines, 430207, Wuhan, China.
Wuhan Institute of Bioengineering · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor necrosis factor receptor-associated factor 3 (TRAF3), an adaptor protein, has significant and varying effects on immunity depending on cell types. The role of TRAF3 in Madin-Darby Canine Kidney Epithelial (MDCK) cell resistance to influenza A virus (IVA) remains elusive. In the present study, CRISPR-Cas9 gene editing technology was used to construct the

Indexed as

CRISPR-Cas9InfluenzaMadin-Darby canine kidney epithelial (MDCK)Tumor necrosis factor receptor-associated factor 3 (TRAF3)

Identifiers

PMID37681145
PMCPMC10481187
OpenAlexW4386034659

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.