ReviewInternational journal of molecular sciences2023
Latest Research of Doped Hydroxyapatite for Bone Tissue Engineering.
Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 88 citations in OpenAlex.
- AI for bioactive materials: From material design to biological applications.Bioactive materials · 2026Review
- Metal-Substituted Hydroxyapatite Nanoparticles as Antimicrobial and Osteogenic Biomaterials for Hard-Tissue Applications.Materials (Basel, Switzerland) · 2026Review
- Preparation and Characterization of Hydroxyapatite from Eggshells via a Basic Route Using Attritor Milling.Nanomaterials (Basel, Switzerland) · 2026Article
- Rapid osteointegration with a strontium-containing hydroxyapatite coating on tantalum by activating Itga6-PI3K/AKT signaling pathway.Materials today. Bio · 2025Article
- Nanoparticles in the treatment of osteoporosis: recent advances in nanoparticles for the treatment of osteoporosis.RSC advances · 2025Review
- Chitosan-Hydrazone-Modified Calcium Phosphate Scaffolds: Fabrication, Characterization, and Drug Delivery Potential.Biomedicines · 2025Article
- Physical and drug- releasing properties of a cement containing simvastatin (SimCeram).BMC oral health · 2025Article
- Sustainable production of osteoinductive CoScientific reports · 2025Article
- New Nanobioceramics Based on Hydroxyapatite for Biomedical Applications: Stability and Properties.Nanomaterials (Basel, Switzerland) · 2025Article
- Fabrication of biocidal materials based on the molecular interactions of tetracycline and quercetin with hydroxyapatite viaHeliyon · 2025Article
- Bacterial Cellulose/Graphene Oxide/Hydroxyapatite Biocomposite: A Scaffold from Sustainable Sources for Bone Tissue Engineering.ACS applied materials & interfaces · 2025Article
- Strontium/magnesium-doped coralline hydroxyapatite for bone regeneration.Regenerative biomaterials · 2025Article
- Impact of Cerium Doping on the Osteogenic Properties of a 3D Biomimetic Piezoelectric Scaffold with Sustained MgInternational journal of nanomedicine · 2025Article
- Preparation and characterization of highly crystalline hydroxyapatite (HAp) from the scales of an anadromous fish (RSC advances · 2024Article
- Three-Dimensionally Printed Bionic Hydroxyapatite (HAp) Ceramic Scaffolds with Different Structures and Porosities: Strength, Biocompatibility, and Biomedical Application Potential.Materials (Basel, Switzerland) · 2024Article
- Exploring the frontiers: The potential and challenges of bioactive scaffolds in osteosarcoma treatment and bone regeneration.Materials today. Bio · 2024Review
- Evaluation of mineral induction ability and cytotoxicity of carbonated hydroxyapatite for pulp tissue regeneration: anRestorative dentistry & endodontics · 2024Article
- Chitosan biomineralized with ions-doped nano-hydroxyapatite tunes osteoblasts metabolism and DNA damage.Journal of biological engineering · 2024Article
- Hybrid Hydroxyapatite-Metal Complex Materials Derived from Amino Acids and Nucleobases.Molecules (Basel, Switzerland) · 2024Review
- Evaluating various properties of nanohydroxyapatite synthesized from eggshells and dual-doped with SiHeliyon · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bone tissue engineering has attracted great interest in the last few years, as the frequency of tissue-damaging or degenerative diseases has increased exponentially. To obtain an ideal treatment solution, researchers have focused on the development of optimum biomaterials to be applied for the enhancement of bioactivity and the regeneration process, which are necessary to support the proper healing process of osseous tissues. In this regard, hydroxyapatite (HA) has been the most widely used material in the biomedical field due to its great biocompatibility and similarity with the native apatite from the human bone. However, HA still presents some deficiencies related to its mechanical properties, which are essential for HA to be applied in load-bearing applications. Bioactivity is another vital property of HA and is necessary to further improve regeneration and antibacterial activity. These drawbacks can be solved by doping the material with trace elements, adapting the properties of the material, and, finally, sustaining bone regeneration without the occurrence of implant failure. Considering these aspects, in this review, we have presented some general information about HA properties, synthesis methods, applications, and the necessity for the addition of doping ions into its structure. Also, we have presented their influence on the properties of HA, as well as the latest applications of doped materials in the biomedical field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.