Evidence map›Paper›PMID 37686135›Full record

ArticleInternational journal of molecular sciences2023

Gut Microbiota Alterations and Their Functional Differences in Depression According to Enterotypes in Asian Individuals.

Sunmin Park, Chen Li, Xuangao Wu, Tianshun Zhang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  13. Gut microbes · 2025
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  16. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sunmin ParkDepartment of Food and Nutrition, Obesity/Diabetes Research Center, Hoseo University, Asan-si 31499, Republic of Korea.ORCID 0000-0002-6092-8340
Chen LiDepartment of Food and Nutrition, Obesity/Diabetes Research Center, Hoseo University, Asan-si 31499, Republic of Korea.
Xuangao WuDepartment of Bioconvergence, Hoseo University, Asan-si 31499, Republic of Korea.ORCID 0000-0002-6293-7363
Tianshun ZhangDepartment of Food and Nutrition, Obesity/Diabetes Research Center, Hoseo University, Asan-si 31499, Republic of Korea.
Hoseo University · KR

Funding

the National Research Foundation of Korea RS-2021-00208567
6 · The paper itself

Abstract

This study aimed to investigate alterations in the gut microbiota of patients with depression compared to those in the gut microbiota of healthy individuals based on enterotypes as a classification framework. Fecal bacteria FASTA/Q samples from 333 Chinese participants, including 107 healthy individuals (Healthy group) and 226 individuals suffering from depression (DP group), were analyzed. The participants were classified into three enterotypes: Bacteroidaceae (ET-B), Lachnospiraceae (ET-L), and Prevotellaceae (ET-P). An α-diversity analysis revealed no significant differences in microbial diversity between the Healthy and DP groups across all enterotypes. However, there were substantial differences in the gut microbial composition for β-diversity, particularly within ET-L and ET-B. The DP group within ET-B exhibited a higher abundance of Proteobacteria, while a linear discriminant analysis (LDA) of the DP group showed an increased relative abundance of specific genera, such as

Indexed as

Gastrointestinal MicrobiomeMicrobiotaAsian PeopleBifidobacteriumBrain-Gut AxisDepressionHumansenterotypeglucose metabolismgut–brain axisgut microbiotanetwork analysis

Identifiers

PMID37686135
PMCPMC10487633
OpenAlexW4386223672

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.