Evidence map›Paper›PMID 37686582›Full record

ArticleCancers2023

Evolution of Patterns of Care and Outcomes in the Real-Life Setting for Patients with Metastatic GIST Treated in Three French Expert Centers over Three Decades.

Maud Toulmonde, Derek Dinart, Mehdi Brahmi, Benjamin Verret, Myriam Jean-Denis, Françoise Ducimetière, Gregoire Desolneux, Pierre Méeus, Jean Palussière, Xavier Buy and 12 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03963544 (Patterns of Care and Outcomes of Patients With METAstatic Gastrointestinal Stromal Tumors), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03963544 completednot on this map

Patterns of Care and Outcomes of Patients With METAstatic Gastrointestinal Stromal Tumors (GIST) in a Real-life Setting: the METAGIST Observational Study

TypeobservationalSponsorInstitut BergoniéRan1990 to 2024Enrolled492ConditionsGastro Intestinal Stromal TumorArmsoral tyrosine-kinase inhibitors (TKI) of KIT and PDGFR as per recommendations
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Clinical impact of primary and secondary KIT mutations on the efficacy of molecular-targeted therapies in gastrointestinal stromal tumors.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 3 institutions in 1 country.

Maud ToulmondeDepartment of Medical Oncology, Institut Bergonié, 33076 Bordeaux, France.
Derek DinartDepartment of Epidemiology and Clinical Research, Institut Bergonié, 33076 Bordeaux, France.
Mehdi BrahmiDepartment of Medical Oncology, Centre Leon Berard, 69373 Lyon, France.
Benjamin VerretDepartment of Medical Oncology, Gustave Roussy, 94800 Villejuif, France.
Myriam Jean-DenisDepartment of Epidemiology and Clinical Research, Centre Leon Berard, 69373 Lyon, France.
Françoise DucimetièreDepartment of Epidemiology and Clinical Research, Centre Leon Berard, 69373 Lyon, France.
Gregoire DesolneuxDepartment of Surgical Oncology, Institut Bergonié, 33076 Bordeaux, France.
Pierre MéeusDepartment of Surgical Oncology, Centre Leon Berard, 69373 Lyon, France.
Jean PalussièreDepartment of Radiodiagnostic and Interventional Radiology, Institut Bergonié, 33076 Bordeaux, France.
Xavier BuyDepartment of Radiodiagnostic and Interventional Radiology, Institut Bergonié, 33076 Bordeaux, France.
Amine BouhamamaDepartment of Radiodiagnostic and Interventional Radiology, Centre Leon Berard, 69373 Lyon, France.
Pauline GillonDepartment of Radiation Oncology, Institut Bergonié, 33076 Bordeaux, France.
Armelle DufresneDepartment of Medical Oncology, Centre Leon Berard, 69373 Lyon, France.
Clémence HénonDepartment of Medical Oncology, Gustave Roussy, 94800 Villejuif, France.
François Le LoarerDepartment of Pathology, Institut Bergonié, 33076 Bordeaux, France.
Marie KaranianDepartment of Pathology, Centre Leon Berard, 69373 Lyon, France.
Carine NgoDepartment of Pathology, Gustave Roussy, 94800 Villejuif, France.ORCID 0000-0002-8172-5876
Simone Mathoulin-PélissierDepartment of Epidemiology and Clinical Research, Institut Bergonié, 33076 Bordeaux, France.
Carine BelleraDepartment of Epidemiology and Clinical Research, Institut Bergonié, 33076 Bordeaux, France.
Axel Le CesneDepartment of Medical Oncology, Gustave Roussy, 94800 Villejuif, France.
Jean Yves BlayDepartment of Medical Oncology, Centre Leon Berard, 69373 Lyon, France.ORCID 0000-0001-7190-120X
Antoine ItalianoDepartment of Medical Oncology, Institut Bergonié, 33076 Bordeaux, France.
Institut Bergonié · FRCentre Léon Bérard · FRInstitut Gustave Roussy · FR

Funding

Pfizer (France) 2015
6 · The paper itself

Abstract

Gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors characterized by

Indexed as

clinical trialslocoregional treatmentsmetastatic GISTreal-life datatyrosine kinase inhibitors

Identifiers

PMID37686582
PMCPMC10487208
OpenAlexW4386254962

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.