Evidence mapPaperPMID 37686758Full record

SynthesisNutrients2023

A Potential Role Exists for Nutritional Interventions in the Chronic Phase of Mild Traumatic Brain Injury, Concussion and Sports-Related Concussion: A Systematic Review.

Tansy Ryan, Sarah Nagle, Ed Daly, Alan J Pearce, Lisa Ryan

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Tansy RyanDepartment of Sport Exercise & Nutrition, Atlantic Technological University, Dublin Road, H91 T8NW Galway City, Galway, Ireland.
Sarah NagleDepartment of Sport Exercise & Nutrition, Atlantic Technological University, Dublin Road, H91 T8NW Galway City, Galway, Ireland.
Ed DalyDepartment of Sport Exercise & Nutrition, Atlantic Technological University, Dublin Road, H91 T8NW Galway City, Galway, Ireland.
Alan J PearceCollege of Sport, Health and Engineering, La Trobe University, Plenty Road and Kingsbury Drive, Melbourne, VIC 3086, Australia.ORCID 0000-0002-9264-9880
Lisa RyanDepartment of Sport Exercise & Nutrition, Atlantic Technological University, Dublin Road, H91 T8NW Galway City, Galway, Ireland.ORCID 0000-0002-5505-7130
Ollscoil na Gaillimhe – University of Galway · IELa Trobe University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mild traumatic brain injury (mTBI) represents a significant burden for individuals, economies, and healthcare systems worldwide. Recovery protocols focus on medication and physiotherapy-based interventions. Animal studies have shown that antioxidants, branched-chain amino acids and omega-3 fatty acids may improve neurophysiological outcomes after TBI. However, there appears to be a paucity of nutritional interventions in humans with chronic (≥1 month) symptomology post-mTBI. This systematic literature review aimed to consolidate evidence for nutrition and dietary-related interventions in humans with chronic mTBI. The review was registered with the International Prospective Register of Systematic Reviews (PROSPERO; CRD42021277780) and conducted following the Preferred Reporting for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Three reviewers searched five databases (PubMed/MEDLINE, Web of Science, SPORTDiscus, CINAHL Complete and Cochrane), which yielded 6164 studies. Nine studies met the inclusion criteria. The main finding was the lack of interventions conducted to date, and a quality assessment of the included studies was found to be fair to good. Due to heterogeneity, a meta-analysis was not feasible. The six nutrition areas identified (omega-3 fatty acids, melatonin, Enzogenol

Indexed as

Brain ConcussionAmino Acids, Branched-ChainAnimalsAntioxidantsAnxietyAnxiety DisordersHumansAmino Acids, Branched-ChainAntioxidantsconcussiondietnutritionrecoverysupplement

Identifiers

PMID37686758
PMCPMC10490336
OpenAlexW4386168733

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.