Evidence map›Paper›PMID 37688748›Full record

SynthesisTissue engineering and regenerative medicine2023

Applications of Bacterial Cellulose-Based Composite Materials in Hard Tissue Regenerative Medicine.

Yingyu Liu, Haiyan Liu, Susu Guo, Jin Qi, Ran Zhang, Xiaoming Liu, Lingxiang Sun, Mingrui Zong, Huaiyi Cheng, Xiuping Wu and 1 more

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Tissue engineering and regenerative medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Biomineral-Based Composite Materials in Regenerative Medicine.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Yingyu Liu *Shanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Haiyan Liu *Shanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Susu Guo *Shanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Jin QiShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Ran ZhangShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Xiaoming LiuShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Lingxiang SunShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Mingrui ZongShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Huaiyi ChengShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Xiuping WuShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China. 77wxp@163.com.
Bing LiShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China. libing-1975@163.com.ORCID 0009-0008-1746-1109
Shanxi Medical University · CN

Funding

Key national science and technology cooperation project of Shanxi Provincial Department of Science and Technology 202204041101004Key Research and Development Plan of Shanxi Province 202102130501002Science and Technology Innovation Leader and Key Talent Team Project of Shanxi Province 202204051002034Scientific Research Project for Returned Overseas Professionals of Shanxi Province 2022-120Shenzhen Knowledge Innovation Program 20210302124085the Program of Higher Education Institutions in Shanxi 2020L0212
6 · The paper itself

Abstract

backgroundCartilage, bone, and teeth, as the three primary hard tissues in the human body, have a significant application value in maintaining physical and mental health. Since the development of bacterial cellulose-based composite materials with excellent biomechanical strength and good biocompatibility, bacterial cellulose-based composites have been widely studied in hard tissue regenerative medicine. This paper provides an overview of the advantages of bacterial cellulose-based for hard tissue regeneration and reviews the recent progress in the preparation and research of bacterial cellulose-based composites in maxillofacial cartilage, dentistry, and bone.

methodA systematic review was performed by searching the PubMed and Web of Science databases using selected keywords and Medical Subject Headings search terms.

resultsIdeal hard tissue regenerative medicine materials should be biocompatible, biodegradable, non-toxic, easy to use, and not burdensome to the human body; In addition, they should have good plasticity and processability and can be prepared into materials of different shapes; In addition, it should have good biological activity, promoting cell proliferation and regeneration. Bacterial cellulose materials have corresponding advantages and disadvantages due to their inherent properties. However, after being combined with other materials (natural/ synthetic materials) to form composite materials, they basically meet the requirements of hard tissue regenerative medicine materials. We believe that it is worth being widely promoted in clinical applications in the future.

conclusionBacterial cellulose-based composites hold great promise for clinical applications in hard tissue engineering. However, there are still several challenges that need to be addressed. Further research is needed to incorporate multiple disciplines and advance biological tissue engineering techniques. By enhancing the adhesion of materials to osteoblasts, providing cell stress stimulation through materials, and introducing controlled release systems into matrix materials, the practical application of bacterial cellulose-based composites in clinical settings will become more feasible in the near future.

Indexed as

Biocompatible MaterialsRegenerative MedicineCartilageCelluloseHumansTissue EngineeringBiocompatible MaterialsCelluloseBacterial celluloseBoneDentistryHard tissueRegenerative medicine

Identifiers

PMID37688748
PMCPMC10645761
OpenAlexW4386580306

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.