Evidence mapPaperPMID 37693191Full record

ArticleRadiology. Cardiothoracic imaging2023

Coronary Artery Vorticity to Predict Functional Plaque Progression in Participants with Type 2 Diabetes Mellitus.

Nobuo Tomizawa, Shinichiro Fujimoto, Tomoya Mita, Daigo Takahashi, Yui Nozaki, Ruiheng Fan, Ayako Kudo, Yuko Kawaguchi, Kazuhisa Takamura, Makoto Hiki and 5 more

Abstract read
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Identifying When Steady-State Flow Simulations In Patient-Specific Coronaries Recapitulate Pulsatile Flow Dynamics.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2024
    Article
  4. Energy loss is related to CT fractional flow reserve progression in type 2 diabetes mellitus patients.American heart journal plus : cardiology research and practice · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Nobuo TomizawaFrom the Department of Radiology (N.T., R.F., K.K.K., S.A.), Department of Cardiovascular Biology and Medicine (S.F., D.T., Y.N., A.K., Y.K., K.T., M.H., T. Minamino), and Department of Diabetes, Endocrinology, and Metabolism (T. Mita, M.K., H.W.), Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.ORCID 0000-0001-6305-1081
Shinichiro FujimotoFrom the Department of Radiology (N.T., R.F., K.K.K., S.A.), Department of Cardiovascular Biology and Medicine (S.F., D.T., Y.N., A.K., Y.K., K.T., M.H., T. Minamino), and Department of Diabetes, Endocrinology, and Metabolism (T. Mita, M.K., H.W.), Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Tomoya MitaFrom the Department of Radiology (N.T., R.F., K.K.K., S.A.), Department of Cardiovascular Biology and Medicine (S.F., D.T., Y.N., A.K., Y.K., K.T., M.H., T. Minamino), and Department of Diabetes, Endocrinology, and Metabolism (T. Mita, M.K., H.W.), Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Daigo TakahashiFrom the Department of Radiology (N.T., R.F., K.K.K., S.A.), Department of Cardiovascular Biology and Medicine (S.F., D.T., Y.N., A.K., Y.K., K.T., M.H., T. Minamino), and Department of Diabetes, Endocrinology, and Metabolism (T. Mita, M.K., H.W.), Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Yui NozakiFrom the Department of Radiology (N.T., R.F., K.K.K., S.A.), Department of Cardiovascular Biology and Medicine (S.F., D.T., Y.N., A.K., Y.K., K.T., M.H., T. Minamino), and Department of Diabetes, Endocrinology, and Metabolism (T. Mita, M.K., H.W.), Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Ruiheng FanFrom the Department of Radiology (N.T., R.F., K.K.K., S.A.), Department of Cardiovascular Biology and Medicine (S.F., D.T., Y.N., A.K., Y.K., K.T., M.H., T. Minamino), and Department of Diabetes, Endocrinology, and Metabolism (T. Mita, M.K., H.W.), Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.ORCID 0000-0003-0328-2472
Ayako KudoFrom the Department of Radiology (N.T., R.F., K.K.K., S.A.), Department of Cardiovascular Biology and Medicine (S.F., D.T., Y.N., A.K., Y.K., K.T., M.H., T. Minamino), and Department of Diabetes, Endocrinology, and Metabolism (T. Mita, M.K., H.W.), Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.ORCID 0000-0001-9194-9358
Yuko KawaguchiFrom the Department of Radiology (N.T., R.F., K.K.K., S.A.), Department of Cardiovascular Biology and Medicine (S.F., D.T., Y.N., A.K., Y.K., K.T., M.H., T. Minamino), and Department of Diabetes, Endocrinology, and Metabolism (T. Mita, M.K., H.W.), Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Kazuhisa TakamuraFrom the Department of Radiology (N.T., R.F., K.K.K., S.A.), Department of Cardiovascular Biology and Medicine (S.F., D.T., Y.N., A.K., Y.K., K.T., M.H., T. Minamino), and Department of Diabetes, Endocrinology, and Metabolism (T. Mita, M.K., H.W.), Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Makoto HikiFrom the Department of Radiology (N.T., R.F., K.K.K., S.A.), Department of Cardiovascular Biology and Medicine (S.F., D.T., Y.N., A.K., Y.K., K.T., M.H., T. Minamino), and Department of Diabetes, Endocrinology, and Metabolism (T. Mita, M.K., H.W.), Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Mika KuritaFrom the Department of Radiology (N.T., R.F., K.K.K., S.A.), Department of Cardiovascular Biology and Medicine (S.F., D.T., Y.N., A.K., Y.K., K.T., M.H., T. Minamino), and Department of Diabetes, Endocrinology, and Metabolism (T. Mita, M.K., H.W.), Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Kanako K KumamaruFrom the Department of Radiology (N.T., R.F., K.K.K., S.A.), Department of Cardiovascular Biology and Medicine (S.F., D.T., Y.N., A.K., Y.K., K.T., M.H., T. Minamino), and Department of Diabetes, Endocrinology, and Metabolism (T. Mita, M.K., H.W.), Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Hirotaka WatadaFrom the Department of Radiology (N.T., R.F., K.K.K., S.A.), Department of Cardiovascular Biology and Medicine (S.F., D.T., Y.N., A.K., Y.K., K.T., M.H., T. Minamino), and Department of Diabetes, Endocrinology, and Metabolism (T. Mita, M.K., H.W.), Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.ORCID 0000-0001-5961-1816
Tohru MinaminoFrom the Department of Radiology (N.T., R.F., K.K.K., S.A.), Department of Cardiovascular Biology and Medicine (S.F., D.T., Y.N., A.K., Y.K., K.T., M.H., T. Minamino), and Department of Diabetes, Endocrinology, and Metabolism (T. Mita, M.K., H.W.), Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Shigeki AokiFrom the Department of Radiology (N.T., R.F., K.K.K., S.A.), Department of Cardiovascular Biology and Medicine (S.F., D.T., Y.N., A.K., Y.K., K.T., M.H., T. Minamino), and Department of Diabetes, Endocrinology, and Metabolism (T. Mita, M.K., H.W.), Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.ORCID 0000-0002-8491-0698

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate whether vorticity could predict functional plaque progression better than high-risk plaque (HRP) and lesion length (LL) in individuals with type 2 diabetes mellitus. Materials and Methods: This single-center prospective study included 61 participants (mean age, 61 years ± 9 [SD]; 43 male participants) who underwent serial coronary CT angiography at 2 years, with 20%-70% stenosis at initial CT between October 2015 and March 2020. The number of the following HRP characteristics was recorded: low attenuation, positive remodeling, spotty calcification, and napkin-ring sign. Vorticity was calculated using a mesh-free simulation. A decrease in CT fractional flow reserve larger than 0.05 indicated functional progression. Models using HRP and LL and vorticity were compared using receiver operating characteristic curve analysis. Results: Of the 94 vessels evaluated, 25 vessels (27%) showed functional progression. Vessels with functional progression showed higher vorticity at distal stenosis (984 sec Conclusion: In participants with type 2 diabetes mellitus, vorticity at distal stenosis was a better predictor of functional plaque progression than HRP and LL.

Indexed as

Computational Fluid DynamicsCoronary ArteryCT AngiographyFractional Flow ReserveFunctional Plaque ProgressionType 2 DiabetesVasculatureVorticity

Identifiers

PMID37693191
PMCPMC10483244

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.